Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.65 |
| ▸ | NPC1 | O15118 | 11/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.65 |
| ▸ | RELA | Q04206 | 2/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2999051 | 0.78 | SMN1; SMN2 (0.78) | RAB9ANPC1ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL14825100 | 0.77 | NPC1 (0.86) | RAB9ANPC1ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL10375494 | 0.73 | RAB9A (0.57) | RAB9ANPC1ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL3761978 | 0.70 | SMN1; SMN2 (0.65) | RAB9ANPC1ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL11489324 | 0.70 | RAB9A (1.00) | RAB9ANPC1ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL3760650 | 0.69 | GLA (1.00) | RAB9ANPC1ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL6033361 | 0.68 | RAB9A (0.55) | RAB9ANPC1ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL18954506 | 0.66 | SMN1; SMN2 (0.66) | RAB9ANPC1ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL4416533 | 0.66 | ALDH1A1 (0.61) | RAB9ANPC1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL2977154 | 0.66 | ALDH1A1 (0.61) | RAB9ANPC1ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962639-B2 | Potassium channel modulators | ABBVIE INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20100305109-A1 | POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305109-A1 | POTASSIUM CHANNEL MODULATORS | KCNQ1, KCNQ2, KCNJ2 | RAB9A 1488/4885NPC1 377/4885ALDH1A1 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.