Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2996389 | 1.00 | CYP1A2 (0.44) | CYP1A2CYP2D6CYP2C19SLC6A4CA1 | |
| SCHEMBL2996386 | 1.00 | CYP1A2 (0.44) | CYP1A2CYP2D6CYP2C19SLC6A4CA1 | |
| SCHEMBL13267800 | 1.00 | CYP1A2 (0.44) | CYP1A2CYP2D6CYP2C19SLC6A4CA1 | |
| SCHEMBL1900910 | 0.80 | CA1 (0.58) | CYP1A2CYP2D6CYP2C19SLC6A4CA1 | |
| SCHEMBL1900477 | 0.80 | CA1 (0.58) | CYP1A2CYP2D6CYP2C19SLC6A4CA1 | |
| SCHEMBL1305495 | 0.80 | CA1 (0.58) | CYP1A2CYP2D6CYP2C19SLC6A4CA1 | |
| SCHEMBL591062 | 0.80 | CA1 (0.58) | CYP1A2CYP2D6CYP2C19SLC6A4CA1 | |
| SCHEMBL13056306 | 0.79 | DPP4 (0.36) | ACHEALDH1A1TDP1MAPTCA7 | |
| SCHEMBL13056307 | 0.79 | DPP4 (0.36) | ACHEALDH1A1TDP1MAPTCA7 | |
| SCHEMBL8914585 | 0.79 | CYP1A2 (0.48) | CYP1A2CYP2D6CYP2C19SLC6A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8350047-B2 | Methods of preparing secondary carbinamine compounds with boronic acids | THADANI AVINASH N (CA) | 2013-01-08 | — | — | US | disclosed |
| US-20100298572-A1 | METHODS OF PREPARING SECONDARY CARBINAMINE COMPOUNDS WITH BORONIC ACIDS | PANASONIC CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| WO-2008119161-A1 | METHODS OF PREPARING SECONDARY CARBINAMINE COMPOUNDS WITH BORONIC ACIDS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298572-A1 | METHODS OF PREPARING SECONDARY CARBINAMINE COMPOUNDS WITH BORONIC ACIDS | C9, BCAT2, SLC1A5 | CYP1A2 541/4885CYP2D6 1030/4885CYP2C19 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.