SCHEMBL375036

SCHEMBL375036

CN(C)C(=O)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.53
DRD3 P35462 3/20 0.53
DRD4 P21917 2/20 0.53
CYP2C9 P11712 2/20 0.45
DRD2 P14416 2/20 0.44
CHRM2 P08172 2/20 0.44
CHRM1 P11229 2/20 0.44
CHRM3 P20309 2/20 0.44
CHRM4 P08173 1/20 0.44
HTT P42858 2/20 0.43
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KCNN4 O15554 2/20 0.43
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
POLB P06746 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
HPGD P15428 1/20 0.42
NR1H2 P55055 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23828847 0.91 DRD4 (0.46) OPRM1DRD3DRD4CYP2C9DRD2
SCHEMBL23828849 0.89 SLC2A1 (0.50) OPRM1DRD3DRD4CYP2C9HTT
SCHEMBL23828851 0.86 KMT2A (0.51) OPRM1DRD3DRD4DRD2KMT2A
SCHEMBL10814384 0.83 OPRM1 (0.53) OPRM1DRD3DRD4CYP2C9DRD2
SCHEMBL5768688 0.80 CHRM2 (0.54) OPRM1DRD3DRD4CYP2C9DRD2
SCHEMBL10814377 0.79 OPRM1 (0.50) OPRM1DRD3DRD4CYP2C9DRD2
SCHEMBL5642972 0.78 KMT2A (0.57) OPRM1DRD3DRD4CYP2C9DRD2
SCHEMBL6073343 0.78 OPRM1 (0.53) OPRM1DRD3DRD4CYP2C9DRD2
SCHEMBL6073374 0.77 CYP1A2 (0.59) OPRM1DRD3DRD4CYP2C9DRD2
SCHEMBL16158180 0.77 OPRM1 (0.51) OPRM1DRD3DRD4CYP2C9DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3017001-B1 CURABLE COMPOSITION AND PROCESS FOR THE MANUFACTURE OF AN EPOXY THERMOSET RHODIA OPERATIONS (FR) 2019-06-19 EP disclosed
US-10077332-B2 Curable composition and process for the manufacture of an epoxy thermoset RHODIA OPERATIONS (FR) 2018-09-18 US disclosed
CN-105377971-B Curable composition and process for making epoxy thermoset 罗地亚经营管理公司 2017-12-12 CN disclosed
CN-102627753-B Comprise the epoxy resin of cycloalphatic diamine curing agent 陶氏环球技术有限责任公司 2017-03-01 CN disclosed
US-20160152764-A1 Curable composition and process for the manufacture of an epoxy thermoset SPECIALTY OPERATIONS FRANCE (FR) 2016-06-02 US disclosed
EP-3017001-A1 CURABLE COMPOSITION AND PROCESS FOR THE MANUFACTURE OF AN EPOXY THERMOSET Rhodia Operations (FR) 2016-05-11 EP disclosed
CN-105377971-A Curable composition and process for making epoxy thermoset RHODIA OPERATIONS 2016-03-02 CN disclosed
EP-2829570-A1 Curable composition and process for the manufacture of an epoxy thermoset Rhodia Operations (FR) 2015-01-28 EP disclosed
WO-2015001061-A1 CURABLE COMPOSITION AND PROCESS FOR THE MANUFACTURE OF AN EPOXY THERMOSET RHODIA OPERATIONS (FR) 2015-01-08 WO disclosed
EP-2410230-B1 method of in situ repair (relining) of pipes or conduits with latent hardeners ELANTAS ITALIA S R L (IT) 2014-02-12 EP disclosed
EP-1408083-B1 CURABLE EPOXY RESIN COMPOSITION DOW CORNING TORAY CO LTD (JP) 2007-09-12 EP disclosed
US-7105614-B2 Curable epoxy resin composition DOW CORNING TORAY SILICONE CO., LTD. (JP) 2006-09-12 US disclosed
US-20050007540-A1 Liquid crystal display cell, display cell, glass substrate for display device and manufacturing method for liquid crystal display cell INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2005-01-13 US disclosed
US-20040198925-A1 Curable epoxy resin composition DOW TORAY CO., LTD. (JP) 2004-10-07 US disclosed
EP-1408083-A1 CURABLE EPOXY RESIN COMPOSITION Dow Corning Toray Silicone Co., Ltd. (JP) 2004-04-14 EP disclosed
US-5759743-A FLOCCULATION; SEPARATION NIPPON PAINT CO., LTD. (JP) 1998-06-02 US disclosed
EP-0624828-A1 DEVELOPER CIRCULATING METHOD IN FLEXOGRAPHIC PLATE MAKING STEP AND APPARATUS FOR PRACTICING THE SAME Nippon Paint Co., Ltd. (JP) 1994-11-17 EP disclosed
US-4703075-A BLEND OF TWO POLYSILOXANES ONE OF WHICH HAS GLYCIDYL UNITS, THE OTHER HAVING AMINO, HYDROXY, CARBOXY OR MERCAPTO GROUPS NTN-RULON INDUSTRIES CO., LTD. (JP) 1987-10-27 US disclosed
EP-0150330-A2 Storage stable, one package, heat curable poly urea/urethane coating compositions AMERICAN CYANAMID COMPANY (US) 1985-08-07 EP disclosed
US-4523003-A Storage stable, one package, heat curable polyurea/urethane coating compositions and method of preparation AMERICAN CYANAMID COMPANY (US) 1985-06-11 US disclosed