⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068062 | 0.78 | ADH1B (0.71) | — | |
| SCHEMBL3605533 | 0.75 | — | — | |
| SCHEMBL271073 | 0.75 | — | — | |
| SCHEMBL8763225 | 0.74 | — | — | |
| SCHEMBL11322360 | 0.74 | ADH1B (0.72) | — | |
| SCHEMBL8764004 | 0.74 | ADH1B (0.72) | — | |
| SCHEMBL11138833 | 0.74 | ADH1B (0.72) | — | |
| SCHEMBL979732 | 0.74 | ADH1B (0.72) | — | |
| SCHEMBL11136512 | 0.74 | ADH1B (0.72) | — | |
| SCHEMBL5104034 | 0.72 | ADH1B (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298392-A1 | Isoindoline Derivatives For The Treatment Of Arrhythmias | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | US | disclosed |
| EP-2049484-A1 | ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS | AstraZeneca AB (SE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008008022-A1 | ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2008-01-17 | — | — | WO | disclosed |
| US-20080015237-A1 | NEW COMPOUNDS I/418 | ASTRAZENECA AB (SE) | 2008-01-17 | — | — | US | disclosed |