Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3747940 | 0.91 | GPR119 (0.43) | GPR119SLC6A4 | |
| SCHEMBL13045249 | 0.82 | AAK1 (0.34) | GPR119SLC6A4AAK1 | |
| SCHEMBL3751560 | 0.76 | STS (0.48) | — | |
| SCHEMBL3752853 | 0.76 | ALDH1A1 (0.39) | AAK1 | |
| SCHEMBL3742666 | 0.75 | AR (0.43) | GPR119AAK1 | |
| SCHEMBL8079018 | 0.75 | CHRM1 (0.54) | GPR119AAK1 | |
| SCHEMBL3743376 | 0.73 | KMT2A (0.38) | AAK1 | |
| SCHEMBL13045267 | 0.72 | RET (0.38) | AAK1 | |
| SCHEMBL3742838 | 0.72 | RET (0.45) | GPR119AAK1 | |
| SCHEMBL10026719 | 0.72 | CHRM2 (0.38) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338450-B2 | Compounds as dipeptidyl peptidase IV (DPP IV) inhibitors | LUPIN LIMITED (IN) | 2012-12-25 | — | — | US | disclosed |
| US-20100291020-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291020-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | DPP4, DPP7, DPP3 | GPR119 48/4885SLC6A4 201/4885CPB2 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.