Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | SCN1A | P35498 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3749490 | 0.90 | ALDH1A1 (0.54) | ALDH1A1CACNA1CCACNA1DKDM4EMAPT | |
| SCHEMBL29358809 | 0.80 | CACNA1C (0.73) | ALDH1A1CACNA1CCACNA1DKDM4EMAPT | |
| SCHEMBL202183 | 0.80 | CACNA1C (0.73) | ALDH1A1CACNA1CCACNA1DKDM4EMAPT | |
| SCHEMBL7951620 | 0.76 | CACNA1C (0.71) | ALDH1A1CACNA1CCACNA1DKDM4EMAPT | |
| SCHEMBL8091424 | 0.76 | CACNA1C (0.70) | ALDH1A1CACNA1CCACNA1DKDM4EMAPT | |
| SCHEMBL3142647 | 0.75 | KDM4E (0.52) | ALDH1A1CACNA1CCACNA1DKDM4EMAPT | |
| SCHEMBL9138577 | 0.75 | CACNA1C (0.67) | ALDH1A1CACNA1CCACNA1DKDM4EMAPT | |
| SCHEMBL16272636 | 0.75 | CACNA1C (0.62) | ALDH1A1CACNA1CCACNA1DKDM4EMAPT | |
| SCHEMBL2815053 | 0.74 | MAPT (0.54) | ALDH1A1CACNA1CCACNA1DKDM4EMAPT | |
| SCHEMBL11524929 | 0.74 | CACNA1C (0.58) | ALDH1A1CACNA1CCACNA1DKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8728705-B2 | Negative photosensitive material, photosensitive board employing the negative photosensitive material, and negative pattern forming method | NITTO DENKO CORPORATION (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20100304298-A1 | NEGATIVE PHOTOSENSITIVE MATERIAL, PHOTOSENSITIVE BOARD EMPLOYING THE NEGATIVE PHOTOSENSITIVE MATERIAL, AND NEGATIVE PATTERN FORMING METHOD | NITTO DENKO CORPORATION (JP) | 2010-12-02 | — | — | US | disclosed |
| EP-2139483-A2 | COMBINATION THERAPIES COMPRISING QUINOXALINE INHIBITORS OF PI3K-ALPHA FOR USE IN THE TREATMENT OF CANCER | Exelixis, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008127594-A2 | COMBINATION THERAPIES COMPRISING QUINOXALINE INHIBITORS OF PI3K-ALPHA FOR USE IN THE TREATMENT OF CANCER | EXELIXIS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |