SCHEMBL375206

SCHEMBL375206

CCc1ccc(Nc2cccc3c2C(=O)c2cccc(Nc4ccc(CC)cc4)c2C3=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 3/20 0.52
▸ APAF1 O14727 1/20 0.52
▸ MITF O75030 1/20 0.52
▸ P2RY4 P51582 2/20 0.52
▸ MAPT P10636 3/20 0.47
▸ MAPK1 P28482 3/20 0.47
▸ RAB9A P51151 3/20 0.47
▸ L3MBTL1 Q9Y468 3/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ EGFR P00533 1/20 0.47
▸ PABPC1 P11940 1/20 0.47
▸ NPC1 O15118 2/20 0.47
▸ LMNA P02545 2/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.47
▸ RPS6KA2 Q15349 1/20 0.44
▸ MAOA P21397 1/20 0.43
▸ TERT O14746 4/20 0.43
▸ BCHE P06276 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375141 0.95 TDP1 (0.51) TDP1APAF1MITFP2RY4MAPT
SCHEMBL9309333 0.88 MAPT (0.51) TDP1APAF1MITFP2RY4MAPT
SCHEMBL3975751 0.87 P2RY4 (0.62) TDP1APAF1MITFP2RY4MAPT
SCHEMBL9309180 0.85 MAPT (0.49) TDP1P2RY4MAPTMAPK1RAB9A
SCHEMBL9308563 0.84 MAPT (0.48) TDP1P2RY4MAPTMAPK1RAB9A
SCHEMBL10938974 0.83 MAPT (0.44) TDP1APAF1MITFP2RY4MAPT
SCHEMBL11496174 0.82 P2RY4 (0.47) TDP1APAF1MITFP2RY4MAPT
SCHEMBL13893952 0.82 P2RY4 (0.57) TDP1APAF1MITFP2RY4MAPT
SCHEMBL1476567 0.82 MAPT (0.52) TDP1P2RY4MAPTMAPK1RAB9A
SCHEMBL10727142 0.82 MAPT (0.52) TDP1APAF1MITFP2RY4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1538154-B1 Quencher composition comprising anthraquinone moieties EXIQON AS (DK) 2008-12-31 — — EP claimed
EP-1831394-A2 PROBES, LIBRARIES AND KITS FOR ANALYSIS OF MIXTURES OF NUCLEIC ACIDS AND METHODS FOR CONSTRUCTING THE SAME Exiqon A/S (DK) 2007-09-12 — — EP claimed
US-20060166238-A1 Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same EXIQON A/S (DK) 2006-07-27 — — US claimed
WO-2006066592-A2 PROBES, LIBRARIES AND KITS FOR ANALYSIS OF MIXTURES OF NUCLEIC ACIDS AND METHODS FOR CONSTRUCTING THE SAME EXIQON A/S (DK) 2006-06-29 — — WO claimed
US-20050227254-A1 Quencher compositions comprising anthraquinone moieties QIAGEN GMBH (DE) 2005-10-13 — — US claimed
EP-1538154-A1 Quencher composition comprising anthraquinone moieties Exiqon A/S (DK) 2005-06-08 — — EP claimed
US-20140227689-A1 NOVEL METHODS FOR QUANTIFICATION OF MICRORNAS AND SMALL INTERFERING RNAS EXIQON A/S (DK) 2014-08-14 — — US disclosed
US-8383344-B2 Methods for quantification of microRNAs and small interfering RNAs EXIQON A/S (DK) 2013-02-26 — — US disclosed
US-8192937-B2 Methods for quantification of microRNAs and small interfering RNAs EXIQON A/S (DK) 2012-06-05 — — US disclosed
EP-1735459-B1 METHODS FOR QUANTIFICATION OF MICRORNAS AND SMALL INTERFERING RNAS EXIQON AS (DK) 2012-01-25 — — EP disclosed
US-20110076675-A1 NOVEL METHODS FOR QUANTIFICATION OF MICRORNAS AND SMALL INTERFERING RNAS EXIQON A/S (DK) 2011-03-31 — — US disclosed
US-7504495-B2 Quencher compositions comprising anthraquinone moieties EXIQON A/S (DK) 2009-03-17 — — US disclosed
EP-1538154-B1 Quencher composition comprising anthraquinone moieties EXIQON AS (DK) 2008-12-31 — — EP disclosed
US-5332521-A Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO., LTD. (JP) 1994-07-26 — — US disclosed
EP-0352637-B1 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO (JP) 1994-03-30 — — EP disclosed
US-5200108-A Flexible substrates supporting layer of liquid crystal material and non-liquid crystalline polymer IDEMITSU KOSAN CO., LTD. (JP) 1993-04-06 — — US disclosed
EP-0352637-A2 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-01-31 — — EP disclosed
US-4702561-A AMINOANTHRAQUINONE BISANIL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-10-27 — — US disclosed
EP-0002104-B1 PLEOCHROIC DYES SUITABLE FOR USE IN SOLUTION WITH LIQUID CRYSTAL MATERIALS FOR ELECTRO-OPTIC DEVICE APPLICATIONS BDH Chemicals Limited (GB) 1982-10-20 — — EP disclosed
EP-0002104-A1 Pleochroic dyes suitable for use in solution with liquid crystal materials for electro-optic device applications BDH Chemicals Limited (GB) 1979-05-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050227254-A1 Quencher compositions comprising anthraquinone moieties ANXA5, SUN2, ANXA3 TDP1 2732/4885APAF1 2128/4885MITF 257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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