Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375206 | 0.95 | TDP1 (0.52) | TDP1APAF1MITFP2RY4MAPT | |
| SCHEMBL28229925 | 0.86 | MAPT (0.44) | TDP1P2RY4MAPTMAPK1RAB9A | |
| SCHEMBL13962358 | 0.83 | P2RY4 (0.48) | TDP1APAF1MITFP2RY4MAPT | |
| SCHEMBL31150829 | 0.83 | UNG (0.47) | TDP1MAPTMAPK1RAB9AL3MBTL1 | |
| SCHEMBL11602052 | 0.83 | P2RY4 (0.50) | TDP1APAF1MITFP2RY4MAPT | |
| SCHEMBL9309333 | 0.83 | MAPT (0.51) | TDP1APAF1MITFP2RY4MAPT | |
| SCHEMBL3975751 | 0.83 | P2RY4 (0.62) | TDP1APAF1MITFP2RY4MAPT | |
| SCHEMBL2612583 | 0.82 | RAB9A (0.54) | TDP1APAF1MITFP2RY4MAPT | |
| SCHEMBL11601873 | 0.82 | MAPT (0.64) | TDP1MAPTMAPK1RAB9AL3MBTL1 | |
| SCHEMBL11604621 | 0.81 | MAPT (0.56) | TDP1MAPTMAPK1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1538154-B1 | Quencher composition comprising anthraquinone moieties | EXIQON AS (DK) | 2008-12-31 | — | — | EP | claimed |
| EP-1831394-A2 | PROBES, LIBRARIES AND KITS FOR ANALYSIS OF MIXTURES OF NUCLEIC ACIDS AND METHODS FOR CONSTRUCTING THE SAME | Exiqon A/S (DK) | 2007-09-12 | — | — | EP | claimed |
| US-20060166238-A1 | Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same | EXIQON A/S (DK) | 2006-07-27 | — | — | US | claimed |
| WO-2006066592-A2 | PROBES, LIBRARIES AND KITS FOR ANALYSIS OF MIXTURES OF NUCLEIC ACIDS AND METHODS FOR CONSTRUCTING THE SAME | EXIQON A/S (DK) | 2006-06-29 | — | — | WO | claimed |
| US-20050227254-A1 | Quencher compositions comprising anthraquinone moieties | QIAGEN GMBH (DE) | 2005-10-13 | — | — | US | claimed |
| EP-1538154-A1 | Quencher composition comprising anthraquinone moieties | Exiqon A/S (DK) | 2005-06-08 | — | — | EP | claimed |
| US-20140227689-A1 | NOVEL METHODS FOR QUANTIFICATION OF MICRORNAS AND SMALL INTERFERING RNAS | EXIQON A/S (DK) | 2014-08-14 | — | — | US | disclosed |
| US-8383344-B2 | Methods for quantification of microRNAs and small interfering RNAs | EXIQON A/S (DK) | 2013-02-26 | — | — | US | disclosed |
| US-8192937-B2 | Methods for quantification of microRNAs and small interfering RNAs | EXIQON A/S (DK) | 2012-06-05 | — | — | US | disclosed |
| EP-1735459-B1 | METHODS FOR QUANTIFICATION OF MICRORNAS AND SMALL INTERFERING RNAS | EXIQON AS (DK) | 2012-01-25 | — | — | EP | disclosed |
| US-20110076675-A1 | NOVEL METHODS FOR QUANTIFICATION OF MICRORNAS AND SMALL INTERFERING RNAS | EXIQON A/S (DK) | 2011-03-31 | — | — | US | disclosed |
| US-7504495-B2 | Quencher compositions comprising anthraquinone moieties | EXIQON A/S (DK) | 2009-03-17 | — | — | US | disclosed |
| EP-1538154-B1 | Quencher composition comprising anthraquinone moieties | EXIQON AS (DK) | 2008-12-31 | — | — | EP | disclosed |
| US-20080076674-A1 | Novel oligonucleotide compositions and probe sequences useful for detection and analysis of non coding RNAs associated with cancer | EXIQON A/S (DK) | 2008-03-27 | — | — | US | disclosed |
| EP-1831394-A2 | PROBES, LIBRARIES AND KITS FOR ANALYSIS OF MIXTURES OF NUCLEIC ACIDS AND METHODS FOR CONSTRUCTING THE SAME | Exiqon A/S (DK) | 2007-09-12 | — | — | EP | disclosed |
| US-20060166238-A1 | Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same | EXIQON A/S (DK) | 2006-07-27 | — | — | US | disclosed |
| WO-2006066592-A2 | PROBES, LIBRARIES AND KITS FOR ANALYSIS OF MIXTURES OF NUCLEIC ACIDS AND METHODS FOR CONSTRUCTING THE SAME | EXIQON A/S (DK) | 2006-06-29 | — | — | WO | disclosed |
| US-20050272075-A1 | Novel methods for quantification of microRNAs and small interfering RNAs | QIAGEN GMBH (DE) | 2005-12-08 | — | — | US | disclosed |
| US-20050227254-A1 | Quencher compositions comprising anthraquinone moieties | QIAGEN GMBH (DE) | 2005-10-13 | — | — | US | disclosed |
| EP-1538154-A1 | Quencher composition comprising anthraquinone moieties | Exiqon A/S (DK) | 2005-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227254-A1 | Quencher compositions comprising anthraquinone moieties | ANXA5, SUN2, ANXA3 | TDP1 2732/4885APAF1 2128/4885MITF 257/4885 |
| US-20080076674-A1 | Novel oligonucleotide compositions and probe sequences useful for detection and analysis of non coding RNAs associated with cancer | SNRPE, SNRPA, NOP56 | TDP1 963/4885APAF1 2279/4885MITF 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.