Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | ICMT | O60725 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036343 | 0.82 | CYP19A1 (0.57) | CYP19A1CYP11B1CYP11B2HPGDMAOB | |
| SCHEMBL10728257 | 0.80 | MRGPRX4 (0.49) | MRGPRX4ARICMTHPGDMAOB | |
| SCHEMBL19612232 | 0.78 | NPC1 (0.53) | HPGDMAOBMAOAHTR2CSLC6A4 | |
| SCHEMBL23588252 | 0.78 | CSNK2A1 (0.55) | MRGPRX4ARICMTSLC6A4 | |
| SCHEMBL3753881 | 0.78 | HPGD (0.51) | CYP19A1CYP11B1CYP11B2MRGPRX4AR | |
| SCHEMBL22784142 | 0.78 | MAOB (0.54) | CYP19A1CYP11B1CYP11B2MAOBMAOA | |
| SCHEMBL4209860 | 0.77 | L3MBTL1 (0.57) | MRGPRX4ARICMTHPGD | |
| SCHEMBL3747216 | 0.77 | GLA (0.52) | MRGPRX4ARICMTSLC6A4 | |
| SCHEMBL14586643 | 0.77 | MAPT (0.61) | MRGPRX4HPGDHTR2CSLC6A4HTR2B | |
| SCHEMBL11360859 | 0.77 | NPC1 (0.56) | MRGPRX4HPGDMAOBMAOAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834039-B2 | Oxadiazole compounds | ABBOTT LABORATORIES (US) | 2010-11-16 | — | — | US | disclosed |
| EP-1915338-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007017754-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2007-02-15 | — | — | WO | disclosed |