Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.48 |
| ▸ | FNTB | P49356 | 3/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methionine SCHEMBL3752287 | 1.00 | FNTA (0.48) | FNTAFNTBPGGT1BLMNANOS2 | |
| Methionine SCHEMBL1278586 | 1.00 | FNTA (0.48) | FNTAFNTBPGGT1BLMNANOS2 | |
| Methionine SCHEMBL6466828 | 0.98 | FNTA (0.47) | FNTAFNTBPGGT1BLMNANOS2 | |
| Methionine SCHEMBL6466827 | 0.98 | FNTA (0.47) | FNTAFNTBPGGT1BLMNANOS2 | |
| SCHEMBL468871 | 0.90 | NOS2 (0.49) | NOS2NOS3NOS1ALDH1A1KDM4E | |
| SCHEMBL468869 | 0.90 | NOS2 (0.49) | NOS2NOS3NOS1ALDH1A1KDM4E | |
| SCHEMBL22769504 | 0.90 | NOS2 (0.49) | NOS2NOS3NOS1ALDH1A1KDM4E | |
| SCHEMBL20185858 | 0.90 | LMNA (0.53) | LMNACA2CA1ALDH1A1NPSR1 | |
| SCHEMBL1332039 | 0.90 | LMNA (0.55) | LMNACA2CA1ALDH1A1NPSR1 | |
| SCHEMBL109681 | 0.90 | LMNA (0.55) | LMNACA2CA1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820640-B2 | administering mixture of allopurinol, ebselen and n-acetylcysteine | SOUND PHARMACEUTICALS INCORPORATED (US) | 2010-10-26 | — | — | US | disclosed |
| US-20040220145-A1 | Methods for treating hearing loss | SOUND PHARMACEUTICALS INCORPORATED | 2004-11-04 | — | — | US | disclosed |