⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3763928 | 0.95 | KDM4E (0.31) | — | |
| SCHEMBL3751652 | 0.85 | — | — | |
| SCHEMBL2809962 | 0.76 | KDM4E (0.38) | — | |
| SCHEMBL2806927 | 0.76 | MEN1 (0.40) | — | |
| SCHEMBL2806930 | 0.76 | MEN1 (0.40) | — | |
| SCHEMBL2809964 | 0.76 | KDM4E (0.38) | — | |
| SCHEMBL2805058 | 0.75 | HSP90AA1 (0.37) | — | |
| SCHEMBL2805054 | 0.75 | HSP90AA1 (0.37) | — | |
| SCHEMBL2808446 | 0.75 | KDM4E (0.39) | — | |
| SCHEMBL2808443 | 0.75 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170464-A2 | [1,10]-PHENANTHROLINE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE OR HAEMATOLOGICAL DISEASES | NOSCIRA, S.A. (ES) | 2010-04-07 | — | — | EP | claimed |
| WO-2008152068-A2 | [1,10]-PHENANTHROLINE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE OR HAEMATOLOGICAL DISEASES | NOSCIRA, S.A. (ES) | 2008-12-18 | — | — | WO | claimed |