Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3752422 | 0.95 | — | — | |
| SCHEMBL3751652 | 0.89 | — | — | |
| SCHEMBL2806927 | 0.79 | MEN1 (0.40) | KDM4EALDH1A1POLBGAAMAPT | |
| SCHEMBL2806930 | 0.79 | MEN1 (0.40) | KDM4EALDH1A1POLBGAAMAPT | |
| SCHEMBL2809962 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1POLBGAAMAPT | |
| SCHEMBL2809964 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1POLBGAAMAPT | |
| SCHEMBL2805058 | 0.78 | HSP90AA1 (0.37) | KDM4EALDH1A1POLBGAAMAPT | |
| SCHEMBL2805054 | 0.78 | HSP90AA1 (0.37) | KDM4EALDH1A1POLBGAAMAPT | |
| SCHEMBL2808446 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1POLBGAAMAPT | |
| SCHEMBL2808443 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1POLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170464-A2 | [1,10]-PHENANTHROLINE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE OR HAEMATOLOGICAL DISEASES | NOSCIRA, S.A. (ES) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008152068-A2 | [1,10]-PHENANTHROLINE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE OR HAEMATOLOGICAL DISEASES | NOSCIRA, S.A. (ES) | 2008-12-18 | — | — | WO | disclosed |