SCHEMBL3752472

SCHEMBL3752472

Cc1cccc(C=C(Br)Br)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
TRPA1 O75762 2/20 0.46
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
KDM4E B2RXH2 5/20 0.39
HPGD P15428 3/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPT P10636 3/20 0.39
GAA P10253 3/20 0.39
POLB P06746 2/20 0.39
HTT P42858 2/20 0.39
PSMD14 O00487 1/20 0.39
USP2 O75604 1/20 0.39
ALOX12 P18054 1/20 0.39
MPI P34949 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27400810 0.86 ALDH1A1 (0.50) ALDH1A1TRPA1GABRA1GABRB2CA12
SCHEMBL5992998 0.81 ALDH1A1 (0.54) ALDH1A1TRPA1GABRA1GABRB2CA12
SCHEMBL14269555 0.80 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDMAPTPOLB
SCHEMBL3763341 0.79 ALDH1A1 (0.52) ALDH1A1TRPA1GABRA1GABRB2CA12
SCHEMBL4890494 0.78 CD44 (0.45) ALDH1A1TRPA1CA12CA1CA2
SCHEMBL1681467 0.76 ALDH1A1 (0.43) ALDH1A1TRPA1GABRA1GABRB2CA12
SCHEMBL5322980 0.75 TLR2 (0.62) ALDH1A1CA12KDM4EHPGDHSD17B10
SCHEMBL19782076 0.74 ALDH1A1 (0.56) ALDH1A1TRPA1GABRA1GABRB2CA12
SCHEMBL5073330 0.74 ALDH1A1 (0.56) ALDH1A1TRPA1GABRA1GABRB2CA12
SCHEMBL172956 0.74 ERN1 (0.61) ALDH1A1TRPA1GABRA1GABRB2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101888993-B Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORP 2013-08-21 CN disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 ALDH1A1 1494/4885TRPA1 568/4885GABRA1 2369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.