Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL3670629 | 0.89 | KMT2A (0.42) | KMT2AKDM2BLMNAHRH3GAA | |
| SCHEMBL3640262 | 0.88 | KMT2A (0.41) | KMT2AKDM2BLMNAHRH3ALDH1A1 | |
| SCHEMBL3637781 | 0.79 | GHSR (0.51) | KMT2AALDH1A1SMN1; SMN2MEN1POLB | |
| SCHEMBL3741368 | 0.77 | HTR3E (0.44) | GAAALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL3739298 | 0.74 | HRH3 (0.39) | KMT2AKDM2BHRH3ALDH1A1KDM4E | |
| SCHEMBL3735610 | 0.71 | KMT2A (0.36) | KMT2AKDM2BALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3637907 | 0.70 | KMT2A (0.44) | KMT2AKDM2BALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3747608 | 0.67 | POLB (0.38) | KMT2ALMNAALDH1A1TSHRMEN1 | |
| SCHEMBL3637861 | 0.67 | KMT2A (0.43) | KMT2AKDM2BALDH1A1KDM4ETSHR | |
| SCHEMBL3752090 | 0.66 | USP2 (0.39) | KMT2AHRH3ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GIPR, GHSR, GLP1R | KMT2A 3646/4885KDM2B 3000/4885LMNA 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.