Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11989218 | 0.84 | NPC1 (0.55) | NPC1PTPN1RAB9AHTR7PLOD2 | |
| SCHEMBL23891716 | 0.81 | NPC1 (0.58) | NPC1PTPN1RAB9AHTR7PLOD2 | |
| SCHEMBL3754394 | 0.80 | MAPT (0.52) | NPC1PTPN1RAB9APLOD2CES1 | |
| SCHEMBL19619388 | 0.80 | MAPT (0.52) | NPC1PTPN1RAB9APLOD2CES1 | |
| Hydrochloric Acid SCHEMBL10431496 | 0.78 | MAPT (0.50) | NPC1PTPN1RAB9APLOD2CES1 | |
| SCHEMBL11218710 | 0.78 | PTPN1 (0.58) | NPC1PTPN1RAB9AHTR7PLOD2 | |
| SCHEMBL2074862 | 0.78 | PLOD2 (0.60) | NPC1PTPN1RAB9AHTR7PLOD2 | |
| SCHEMBL7793888 | 0.77 | MAPT (0.33) | NPC1RAB9ACES1LMNAKMT2A | |
| SCHEMBL29568260 | 0.77 | NPC1 (0.47) | NPC1PTPN1RAB9AHTR7PLOD2 | |
| SCHEMBL10770849 | 0.75 | ALDH1A1 (0.60) | RAB9AHSD11B1CA1CA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060954-B1 | DERIVATIVES OF FLUOROPHENACYL AMINES AND THEIR THERAPEUTIC USE | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1984-08-15 | — | — | EP | claimed |