Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.52 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TDO2 | P48775 | 2/20 | 0.44 |
| ▸ | GAK | O14976 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762383 | 0.79 | EGLN3 (0.57) | PDGFRBPDGFRAEGLN3MAPT | |
| SCHEMBL3756602 | 0.76 | SLC40A1 (0.52) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL3520899 | 0.75 | SMN1; SMN2 (0.55) | PDGFRBPDGFRAPARP1CA12CA1 | |
| SCHEMBL1073348 | 0.74 | KDM4E (0.67) | PDGFRBPDGFRAEGLN3PARP1KDM4E | |
| SCHEMBL30238107 | 0.74 | KDM4E (0.67) | PDGFRBPDGFRAEGLN3PARP1KDM4E | |
| SCHEMBL31316511 | 0.72 | KDM4E (0.65) | PDGFRBPDGFRAEGLN3PARP1KDM4E | |
| SCHEMBL30238011 | 0.72 | KDM4E (0.65) | PDGFRBPDGFRAEGLN3PARP1KDM4E | |
| SCHEMBL28421700 | 0.72 | KDM4E (0.65) | PDGFRBPDGFRAEGLN3PARP1KDM4E | |
| SCHEMBL30238255 | 0.70 | PDGFRB (0.69) | PDGFRBPDGFRAKDM4EFYN | |
| SCHEMBL17415836 | 0.70 | MAPT (0.58) | KDM4ECA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305154-A1 | Prolyl Hydroxylase Inhibitors | GLAXOSMITHKLINE LLC | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305154-A1 | Prolyl Hydroxylase Inhibitors | HIF1AN, EGLN3, EGLN2 | PDGFRB 693/4885PDGFRA 363/4885EGLN3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.