SCHEMBL3755558

SCHEMBL3755558

Oc1ccc(C=C(Cl)Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.54
ESR2 Q92731 5/20 0.54
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
THRB P10828 1/20 0.50
CISD1 Q9NZ45 1/20 0.50
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 2/20 0.48
ALDH5A1 P51649 1/20 0.48
ABAT P80404 1/20 0.48
MAPT P10636 2/20 0.46
APP P05067 1/20 0.46
NQO2 P16083 1/20 0.45
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA3 P07451 2/20 0.44
CA4 P22748 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28728616 0.80 TP53 (0.43) ESR1ESR2MEN1KMT2ATHRB
SCHEMBL3753407 0.79 ESR1 (0.50) ESR1ESR2MEN1KMT2ATHRB
SCHEMBL3752596 0.79 ESR1 (0.50) ESR1ESR2MEN1KMT2ATHRB
SCHEMBL3752599 0.79 ESR1 (0.50) ESR1ESR2MEN1KMT2ATHRB
SCHEMBL3753409 0.79 ESR1 (0.50) ESR1ESR2MEN1KMT2ATHRB
SCHEMBL5056133 0.78 FBP1 (0.54) ALDH1A1PTGS2LMNACYP3A4HSD17B10
SCHEMBL9003798 0.77 ESR1 (0.60) ESR1ESR2MEN1KMT2ATHRB
SCHEMBL8854633 0.77 ESR1 (0.60) ESR1ESR2MEN1KMT2ATHRB
SCHEMBL9861448 0.76 CYP2A6 (0.46) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL7765455 0.76 CYP2A6 (0.42) MEN1KMT2AALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107750264-B Rubber composition containing main chain benzoxazine and preparation method thereof 可隆工业株式会社 2020-05-05 CN claimed
CN-107750264-A Rubber composition containing main chain benzoxazine and preparation method thereof 可隆工业株式会社 2018-03-02 CN claimed
US-4163833-A FROM BISPHENOL, ALKALI METAL HYDROXIDE, WATER, METHYLENE HALIDE, PHASE TRANSFER CATALYST GENERAL ELECTRIC COMPANY (US) 1979-08-07 US claimed
JP-58144487-A None JP disclosed
WO-2024024602-A1 RESIN OBTAINED FROM CYCLIC DIOL COMPOUND, AND OPTICAL LENS CONTAINING SAME 三菱瓦斯化学株式会社 2024-02-01 WO disclosed
WO-2024019028-A1 THERMOPLASTIC RESIN AND OPTICAL MEMBER 三菱瓦斯化学株式会社 2024-01-25 WO disclosed
WO-2023195505-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME 三菱瓦斯化学株式会社 2023-10-12 WO disclosed
WO-2023195504-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME 三菱瓦斯化学株式会社 2023-10-12 WO disclosed
CN-114442428-A Photosensitive resin composition, and color filter and display device using same 住华科技股份有限公司 2022-05-06 CN disclosed
CN-109777246-B Water-resistant single-component primer and preparation method thereof 深圳市康利邦科技有限公司 2022-05-03 CN disclosed
CN-110452372-A It is functionalized phenylene ether oligomer, the curable compositions comprising it and thermoset composition and its product and preparation method SABIC GLOBAL TECHNOLOGIES BV 2019-11-15 CN disclosed
US-4452933-A Stabilized polyester-polycarbonate blends and stabilization process therefor GENERAL ELECTRIC COMPANY (US) 1984-06-05 US disclosed
JP-S58144487-A PREPARATION OF DICHLOROETHENYL COMPOUND SHIYOUNO TAMIE 1983-08-27 JP disclosed
US-4345050-A Block copolymers of polyphenylene oxides and polyformals on non-sterically-hindered dihydric phenols GENERAL ELECTRIC COMPANY (US) 1982-08-17 US disclosed
US-4273717-A Monocapped bisphenol salts and method of making GENERAL ELECTRIC COMPANY (US) 1981-06-16 US disclosed
US-4254252-A Cyclic polyformals and method for making GENERAL ELECTRIC COMPANY (US) 1981-03-03 US disclosed
EP-0015860-A1 Process for the preparation of polyglycidyl ethers of polyphenols RHONE-POULENC CHIMIE DE BASE (FR) 1980-09-17 EP disclosed
US-4220805-A Linear dimers of bisphenols and method for making GENERAL ELECTRIC COMPANY (US) 1980-09-02 US disclosed
US-4216305-A INJECTION MOLDABLE HAVING REDUCED GLASS TRANSITION TEMPERATURE GENERAL ELECTRIC COMPANY (US) 1980-08-05 US disclosed
US-4163833-A FROM BISPHENOL, ALKALI METAL HYDROXIDE, WATER, METHYLENE HALIDE, PHASE TRANSFER CATALYST GENERAL ELECTRIC COMPANY (US) 1979-08-07 US disclosed