Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9985259 | 0.82 | ALDH1A1 (0.50) | RAB9ANPC1TDP1MAPTKDM4E | |
| SCHEMBL28728616 | 0.78 | TP53 (0.43) | MAPTKDM4EPOLBNPSR1CA1 | |
| SCHEMBL10594845 | 0.77 | ALDH1A1 (0.53) | CYP2A6RAB9ANPC1SMN1; SMN2TDP1 | |
| SCHEMBL3755558 | 0.76 | ESR1 (0.54) | RAB9ANPC1MAPTKDM4ERECQL | |
| SCHEMBL3338993 | 0.76 | CYP2A6 (0.48) | CYP2A6RAB9ANPC1SMN1; SMN2TDP1 | |
| SCHEMBL5056133 | 0.76 | FBP1 (0.54) | CYP2A6L3MBTL1ALDH1A1PTGS2GRIN2D | |
| SCHEMBL17368414 | 0.75 | AKR1C3 (0.45) | CYP2A6RAB9ANPC1SMN1; SMN2TDP1 | |
| SCHEMBL9160388 | 0.75 | NFE2L2 (0.39) | CYP2A6RAB9ANPC1SMN1; SMN2TDP1 | |
| SCHEMBL9160393 | 0.75 | NFE2L2 (0.39) | CYP2A6RAB9ANPC1SMN1; SMN2TDP1 | |
| SCHEMBL10831971 | 0.74 | CYP2A6 (0.46) | CYP2A6RAB9ANPC1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032062-B2 | HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |
| EP-0396113-A2 | Grafted olefin copolymers and polycarbonate blends modified with a grafted olefin copolymer | THE DOW CHEMICAL COMPANY (US) | 1990-11-07 | — | — | EP | disclosed |
| EP-0393641-A2 | Pyridazinone derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1990-10-24 | — | — | EP | disclosed |
| EP-0032062-B1 | HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1985-04-03 | — | — | EP | disclosed |
| US-4345054-A | High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| EP-0032062-A2 | High-molecular-weight novolak substituted phenolic resins and their preparation | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1981-07-15 | — | — | EP | disclosed |