Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4564362 | 0.86 | HPGD (0.68) | ALDH1A1NOTUMHPGDMEN1KMT2A | |
| SCHEMBL563342 | 0.83 | ALDH1A1 (0.73) | ALDH1A1HPGDSMN1; SMN2GAAMAPK1 | |
| SCHEMBL9830088 | 0.83 | NOTUM (0.63) | ALDH1A1NOTUMMEN1KMT2ANPC1 | |
| SCHEMBL4611029 | 0.83 | ALDH1A1 (0.68) | ALDH1A1NOTUMMEN1KMT2ANPC1 | |
| SCHEMBL10029560 | 0.81 | TSHR (0.47) | HPGDMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL14736736 | 0.80 | NOTUM (0.63) | ALDH1A1NOTUMMEN1KMT2ANPC1 | |
| SCHEMBL14736867 | 0.78 | NOTUM (0.56) | ALDH1A1NOTUMMEN1KMT2ANPC1 | |
| SCHEMBL629128 | 0.77 | MAPT (0.47) | HPGDMEN1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL2089122 | 0.76 | RAB9A (0.69) | ALDH1A1NOTUMHPGDMEN1KMT2A | |
| SCHEMBL15452657 | 0.75 | ALDH1A1 (0.67) | ALDH1A1HPGDMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842324-B2 | Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers | SENOMYX, INC. (US) | 2010-11-30 | — | — | US | disclosed |
| CN-101228115-A | Bis-aromatic amides and their uses as sweet flavor modifiers, tastants and taste enhancers | SENOMYX INC (US) | 2008-07-23 | — | — | CN | disclosed |
| EP-1907353-A2 | BIS-AROMATIC AMIDES AND THEIR USES AS SWEET FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx Inc. (US) | 2008-04-09 | — | — | EP | disclosed |
| US-20070003680-A1 | Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers | SENOMYX, INC. | 2007-01-04 | — | — | US | disclosed |
| WO-2006138512-A2 | BIS-AROMATIC AMIDES AND THEIR USES AS SWEET FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-12-28 | — | — | WO | disclosed |