Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2592720 | 0.84 | HTR7 (0.56) | FFAR1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL3760956 | 0.79 | CNR2 (0.49) | FFAR1ERN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2587585 | 0.78 | SELP (0.47) | FFAR1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL8339408 | 0.77 | HTR7 (0.41) | FFAR1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL8710187 | 0.76 | PPARA (0.52) | PPARGPPARA | |
| SCHEMBL908271 | 0.75 | ABL1 (0.59) | SMN1; SMN2NPC1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL31225595 | 0.74 | L3MBTL1 (0.48) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL31053236 | 0.74 | ABL1 (0.56) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL15056738 | 0.74 | ABL1 (0.56) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL4182154 | 0.74 | CYP1A1 (0.61) | FFAR1SMN1; SMN2ALDH1A1PPARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842324-B2 | Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers | SENOMYX, INC. (US) | 2010-11-30 | — | — | US | disclosed |
| EP-1907353-A2 | BIS-AROMATIC AMIDES AND THEIR USES AS SWEET FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx Inc. (US) | 2008-04-09 | — | — | EP | disclosed |
| US-20070003680-A1 | Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers | SENOMYX, INC. | 2007-01-04 | — | — | US | disclosed |
| WO-2006138512-A2 | BIS-AROMATIC AMIDES AND THEIR USES AS SWEET FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-12-28 | — | — | WO | disclosed |