Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451 | 0.98 | THRB (0.44) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL2637971 | 0.96 | THRB (0.43) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL5264945 | 0.96 | THRB (0.43) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL5446418 | 0.96 | THRB (0.43) | THRBTSHRALDH1A1TP53CYP3A4 | |
| Methacrylic Acid SCHEMBL4886913 | 0.95 | THRB (0.40) | THRBTSHRALDH1A1TP53CYP3A4 | |
| Ethylene Glycol SCHEMBL2356475 | 0.95 | THRB (0.42) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL443709 | 0.94 | THRB (0.44) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL2764467 | 0.94 | THRB (0.44) | THRBTSHRALDH1A1TP53CYP3A4 | |
| Methacrylic Acid SCHEMBL1673561 | 0.93 | THRB (0.39) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL2511404 | 0.93 | THRB (0.43) | THRBTSHRALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838188-B2 | Electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20070231720-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2007-10-04 | — | — | US | disclosed |