Methacrylic Acid

SCHEMBL4886913

C=C(C)C(=O)O.C=C(C)C(=O)OCC(CC)(CO)CO.CCC(CO)(CO)CO.CCC(CO)(CO)CO

nearest known ligand 0.40

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	THRB	P10828	2/20	0.40

▸	TSHR	P16473	3/20	0.39

▸	ALDH1A1	P00352	3/20	0.37

▸	TP53	P04637	1/20	0.37

▸	CYP3A4	P08684	1/20	0.37

▸	MAPK1	P28482	1/20	0.37

▸	SMN1; SMN2	Q16637	1/20	0.37

▸	HIF1A	Q16665	1/20	0.37

▸	POLB	P06746	1/20	0.31

▸	APEX1	P27695	1/20	0.31

▸	HTT	P42858	1/20	0.31

▸	TDP1	Q9NUW8	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Methacrylic Acid SCHEMBL1673561	0.98	THRB (0.39)	THRBTSHRALDH1A1TP53CYP3A4
Methacrylic Acid SCHEMBL10790154	0.97	THRB (0.40)	THRBTSHRALDH1A1TP53CYP3A4
Methacrylic Acid SCHEMBL8749522	0.97	THRB (0.40)	THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL3756979	0.95	THRB (0.43)	THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL30451	0.93	THRB (0.44)	THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL2637971	0.91	THRB (0.43)	THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL5264945	0.91	THRB (0.43)	THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL5446418	0.91	THRB (0.43)	THRBTSHRALDH1A1TP53CYP3A4
Ethylene Glycol SCHEMBL2356475	0.90	THRB (0.42)	THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL443709	0.90	THRB (0.44)	THRBTSHRALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20080097072-A1	Optical Semiconductor Sealing Material	IDEMITSU KOSAN CO., LTD. (JP)	2008-04-24	—	—	US	disclosed