SCHEMBL3757040

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3756899	0.87	CDK2 (0.57)	IGF1RPRKD3LCKCSF1RROS1
	SCHEMBL3755319	0.86	CDK2 (0.57)	IGF1REGFRPRKD3LCKCSF1R
	SCHEMBL3767817	0.84	IGF1R (0.56)	IGF1REGFRABL1PRKD3MAP4K4
	SCHEMBL3766723	0.84	IGF1R (0.55)	IGF1REGFRABL1PRKD3MAP4K4
	SCHEMBL3762802	0.82	ALK (0.53)	IGF1REGFRABL1PRKD3MAP4K4
	SCHEMBL3763966	0.80	IGF1R (0.52)	IGF1REGFRABL1PRKD3MAP4K4
	SCHEMBL3760802	0.80	CDK2 (0.47)	IGF1REGFRABL1PRKD3MAP4K4
	SCHEMBL3762013	0.80	CDK2 (0.62)	IGF1REGFRKDRGSK3BCDK2
	SCHEMBL3759158	0.79	CDK2 (0.51)	IGF1REGFRABL1MAP4K4LCK
	SCHEMBL3761151	0.78	CDK2 (0.56)	IGF1REGFRINSRCDK2CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.