SCHEMBL3757478

SCHEMBL3757478

CCCCCCCCCCCCCCCCO[C@@H](COCc1ccccc1)COC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 3/20 0.50
PLA2G10 O15496 1/20 0.50
PLA2G2A P14555 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
TLR2 O60603 4/20 0.48
PRKCA P17252 1/20 0.47
PRKCE Q02156 1/20 0.47
PRKCQ Q04759 1/20 0.47
PRKCD Q05655 1/20 0.47
CETP P11597 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13058704 1.00 TBXAS1 (0.50) TBXAS1PLA2G10PLA2G2AALDH1A1LMNA
SCHEMBL4748865 0.94 CNR1 (0.53) TBXAS1PRKCAPRKCEPRKCQPRKCD
SCHEMBL31421978 0.91 TLR2 (0.50) PLA2G10PLA2G2ATLR2CETP
SCHEMBL1101589 0.88 ALDH1A1 (0.68) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL9210754 0.88 ALDH1A1 (0.68) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL1092063 0.88 ALDH1A1 (0.68) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL9206562 0.88 ALDH1A1 (0.68) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL1117789 0.88 ALDH1A1 (0.68) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL20714687 0.88 ALDH1A1 (0.68) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL18954214 0.88 ALDH1A1 (0.68) ALDH1A1LMNATLR2PRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100297156-A1 ANALOGUES OF PHOSPHATIDYLINOSITOL MANNOSIDES INDUSTRIAL RESEARCH LIMITED (NZ) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100297156-A1 ANALOGUES OF PHOSPHATIDYLINOSITOL MANNOSIDES PIK3CA, PIK3CB, PIK3CG TBXAS1 624/4885PLA2G10 44/4885PLA2G2A 103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.