Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11720560 | 0.90 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL3754325 | 0.77 | HSD11B1 (0.56) | HSD11B1 | |
| SCHEMBL17210852 | 0.76 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL2793986 | 0.75 | HSD11B1 (0.67) | HSD11B1 | |
| SCHEMBL18493703 | 0.75 | HSD11B1 (0.67) | HSD11B1 | |
| SCHEMBL18503673 | 0.75 | HSD11B1 (0.67) | HSD11B1 | |
| SCHEMBL2650273 | 0.74 | — | — | |
| SCHEMBL30537390 | 0.70 | EPHX1 (0.48) | — | |
| SCHEMBL8908505 | 0.70 | TSHR (0.39) | — | |
| SCHEMBL2566815 | 0.70 | KMT2A (0.39) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962639-B2 | Potassium channel modulators | ABBVIE INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20100305109-A1 | POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305109-A1 | POTASSIUM CHANNEL MODULATORS | KCNQ1, KCNQ2, KCNJ2 | HSD11B1 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.