Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1066268 | 0.91 | TSHR (0.42) | TSHREPHX2BRD4MEN1KMT2A | |
| SCHEMBL10519951 | 0.79 | BRD4 (0.42) | TSHREPHX2BRD4KMT2AHSD17B10 | |
| SCHEMBL3753078 | 0.79 | MGAM (0.43) | EPHX2KMT2AHSD17B10MGAMGAA | |
| SCHEMBL14388470 | 0.78 | TSHR (0.37) | TSHREPHX2BRD4MEN1KMT2A | |
| SCHEMBL3631878 | 0.77 | — | — | |
| SCHEMBL2747443 | 0.77 | HSD11B1 (0.57) | TSHREPHX2BRD4MEN1KMT2A | |
| SCHEMBL10389690 | 0.75 | CYP2D6 (0.40) | TSHREPHX2BRD4MEN1KMT2A | |
| SCHEMBL23567008 | 0.74 | CHRNB2 (0.48) | TSHRBRD4MEN1KMT2A | |
| SCHEMBL13390625 | 0.74 | MEN1 (0.41) | TSHRBRD4MEN1KMT2A | |
| SCHEMBL16229100 | 0.74 | HSD11B1 (0.44) | TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658923-A | USED IN TREATING DISEASES RELATED TO SIGMA-RECEPTOR, SUCH AS SCHIZOPHRENIA | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-08-19 | — | — | US | disclosed |