SCHEMBL3757875

SCHEMBL3757875

CCCCCC[SiH2]OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
THRB P10828 1/20 0.38
CA2 P00918 1/20 0.31
SMPD1 P17405 1/20 0.31
DNM1 Q05193 6/20 0.31
ALDH1A1 P00352 3/20 0.31
LMNA P02545 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HSD17B10 Q99714 1/20 0.31
SLC22A1 O15245 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27499960 1.00 TSHR (0.38) TSHRTHRBCA2SMPD1DNM1
SCHEMBL27959342 1.00 TSHR (0.38) TSHRTHRBCA2SMPD1DNM1
SCHEMBL27781685 1.00 TSHR (0.38) TSHRTHRBCA2SMPD1DNM1
SCHEMBL27959511 1.00 TSHR (0.38) TSHRTHRBCA2SMPD1DNM1
SCHEMBL6009905 1.00 TSHR (0.38) TSHRTHRBCA2SMPD1DNM1
SCHEMBL8678585 0.98 TSHR (0.33) TSHRTHRB
SCHEMBL28137329 0.94 TSHR (0.33) TSHRTHRBSMPD1ALDH1A1LMNA
SCHEMBL705323 0.90 LMNA (0.30) TSHRLMNA
SCHEMBL929341 0.90
SCHEMBL1123039 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531492-A Amino silane modifies cataloid dispersion liquid and its manufacture method 日产化学工业株式会社 2018-01-02 CN disclosed
CN-107141313-A Transparent oxide electrode and its production method that surface modifier, surface for transparent oxide electrode are modified 信越化学工业株式会社 2017-09-08 CN disclosed
CN-106854368-A Inorganic particle silicone composites, the dispersion comprising compound and solid material and preparation method 信越化学工业株式会社 2017-06-16 CN disclosed
CN-106854367-A Rubber composition and its product of solidification 信越化学工业株式会社 2017-06-16 CN disclosed
US-20140234543-A1 METHOD OF MANUFACTURING COATED SUBSTRATE ASAHI GLASS COMPANY, LIMITED (JP) 2014-08-21 US disclosed
CN-103848859-A Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing same SHINETSU CHEMICAL CO 2014-06-11 CN disclosed
CN-101812304-B Liquid crystal aligning agent, liquid crystal display device and fabricating method thereof JSR CO LTD 2014-03-19 CN disclosed
CN-101952218-B Curable polymer concrete mixture BYK CHEMIE GMBH 2013-12-04 CN disclosed
US-8512855-B2 Self-cleaning member and coating composition TOTO LTD. (JP) 2013-08-20 US disclosed
CN-101952218-A Curable polymer concrete mixture BYK CHEMIE GMBH 2011-01-19 CN disclosed
US-20100304120-A1 Self-cleaning member and coating composition TOTO LTD. (JP) 2010-12-02 US disclosed
CN-101812304-A Liquid crystal aligning agent, liquid crystal display device and manufacture method thereof JSR CO LTD 2010-08-25 CN disclosed
US-7569330-B2 Method for manufacturing pattern of light shielding layer and pattern forming body of light shielding layer DAI NIPPON PRINTING CO., LTD. (JP) 2009-08-04 US disclosed
US-20040027514-A1 Method for manufacturing pattern of light shielding layer and pattern forming body of light shielding layer DAI NIPPON PRINTING CO., LTD. (JP) 2004-02-12 US disclosed