Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 6/20 | 0.43 |
| ▸ | PLG | P00747 | 5/20 | 0.43 |
| ▸ | PLAT | P00750 | 3/20 | 0.43 |
| ▸ | DHODH | Q02127 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3750445 | 0.90 | EIF4E (0.43) | PLAUPLGPLATDHODHKDM4E | |
| SCHEMBL3757716 | 0.90 | EIF4E (0.39) | DHODHKDM4EALDH1A1HPGDEIF4E | |
| SCHEMBL3753505 | 0.87 | ALDH1A1 (0.43) | PLAUPLGDHODHKDM4EALDH1A1 | |
| SCHEMBL3747340 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1HPGDEIF4E | |
| SCHEMBL3753803 | 0.84 | ALDH1A1 (0.43) | DHODHKDM4EALDH1A1HPGDEIF4E | |
| SCHEMBL3754215 | 0.84 | KDM4E (0.40) | DHODHKDM4EALDH1A1HPGDEIF4E | |
| SCHEMBL3759586 | 0.82 | HTT (0.47) | DHODHKDM4EALDH1A1HPGDPDCD1 | |
| SCHEMBL3749641 | 0.81 | DHODH (0.45) | DHODHKDM4EALDH1A1HPGDPDCD1 | |
| SCHEMBL3757999 | 0.81 | PPARG (0.35) | KDM4EALDH1A1PPARGPDCD1CD274 | |
| SCHEMBL3755130 | 0.81 | KMO (0.44) | DHODHKDM4EALDH1A1HPGDEIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298221-A1 | 2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-25 | — | — | US | disclosed |
| US-20100298221-A1 | 2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-25 | — | — | US | disclosed |
| US-20100298221-A1 | 2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-25 | — | — | US | disclosed |
| WO-2008031501-A2 | 2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298221-A1 | 2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF | NAPRT, PNPO, FABP3 | PLAU 1022/4885PLG 436/4885PLAT 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.