SCHEMBL3758136

SCHEMBL3758136

CC(O)COC(CO)Cc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.35
PRKCG P05129 2/20 0.33
PRKCB P05771 2/20 0.33
PRKCA P17252 2/20 0.33
PRKCH P24723 2/20 0.33
PRKCE Q02156 2/20 0.33
PRKCD Q05655 2/20 0.33
KMT2A Q03164 2/20 0.33
CLCN2 P51788 1/20 0.33
POLB P06746 1/20 0.33
LMNA P02545 2/20 0.33
HMGB1 P09429 1/20 0.32
ALDH1A1 P00352 3/20 0.31
TSHR P16473 2/20 0.31
SCN9A Q15858 1/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.31
HPGD P15428 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17961587 0.80 FOLH1 (0.43) FOLH1KMT2ACLCN2POLBLMNA
Trimethylammonium SCHEMBL28124204 0.78 FOLH1 (0.41) FOLH1KMT2ACLCN2POLBLMNA
SCHEMBL15901933 0.76 POLB (0.33) POLBTDP1
SCHEMBL3671508 0.76 GABRA1 (0.47) FOLH1KMT2ACLCN2POLBLMNA
SCHEMBL11216383 0.76 SCN9A (0.43) FOLH1KMT2ACLCN2HMGB1ALDH1A1
SCHEMBL901261 0.76 GABRA1 (0.50) FOLH1KMT2ACLCN2LMNAHMGB1
SCHEMBL18334881 0.74
SCHEMBL6558527 0.74 FOLH1 (0.45) FOLH1KMT2ACLCN2HMGB1ALDH1A1
SCHEMBL14764725 0.73 PRKCG (0.33) FOLH1PRKCGPRKCBPRKCAPRKCH
SCHEMBL10392101 0.72 CLCN2 (0.40) FOLH1KMT2ACLCN2POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2026955-B1 LAMINATE MATERIAL NU CLEER SYSTEMS LTD (NZ) 2018-02-07 EP disclosed
US-9168693-B2 Laminate material NU CLEER SYSTEMS LIMITED (NZ) 2015-10-27 US disclosed
US-20130105070-A1 LAMINATE MATERIAL NU CLEER SYSTEMS LIMITED (NZ) 2013-05-02 US disclosed
US-20100297403-A1 LAMINATE MATERIAL NU CLEER SYSTEMS LIMITED (NZ) 2010-11-25 US disclosed