Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29381766 | 1.00 | MAPT (0.53) | MAPTIDO1NPSR1CYP1A2CYP2D6 | |
| Pyridine SCHEMBL6430496 | 0.88 | NPC1 (0.44) | MAPTIDO1NPSR1CYP1A2CYP2D6 | |
| SCHEMBL571925 | 0.86 | MAPT (0.46) | MAPTIDO1NPSR1CYP1A2CYP2D6 | |
| SCHEMBL28389620 | 0.77 | CYP19A1 (0.59) | MAPTNPC1MEN1POLBKMT2A | |
| SCHEMBL3433118 | 0.77 | ALDH1A1 (0.51) | MAPTMEN1KMT2ACYP2A6KDM4E | |
| SCHEMBL8872319 | 0.76 | GAA (0.53) | NPSR1CYP1A2MAPK1CYP2C19MEN1 | |
| SCHEMBL28391367 | 0.76 | DAO (0.49) | MAPTNPSR1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL29548054 | 0.76 | GRIN2D (0.53) | MAPTIDO1NPSR1CYP1A2CYP2D6 | |
| SCHEMBL5200706 | 0.76 | KDM4E (0.53) | MAPTNPC1MEN1KMT2AKDM4E | |
| SCHEMBL28395179 | 0.76 | PIN1 (0.49) | MAPTNPC1POLBKMT2AFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 475 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12535477-B2 | Single-molecule electronic multiplex nanopore immunoassays for biomarker detection | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2026-01-27 | — | — | US | claimed |
| EP-3826960-B1 | SINGLE-MOLECULE ELECTRONIC MULTIPLEX NANOPORE IMMUNOASSAYS FOR BIOMARKER DETECTION | UNIV COLUMBIA (US) | 2024-12-18 | — | — | EP | claimed |
| EP-4192982-A2 | COMPOSITIONS AND METHODS FOR THE DETECTION OF SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-2), INFLUENZA A, AND INFLUENZA B | F. Hoffmann-La Roche AG (CH) | 2023-06-14 | — | — | EP | claimed |
| CN-111646931-B | Chiral 3-indolyl-3, 3' -disubstituted oxoindole compound and preparation method thereof | 成都大学 | 2023-03-14 | — | — | CN | claimed |
| WO-2022066647-A1 | USE OF CRISPR-CAS ENDONUCLEASES FOR PLANT GENOME ENGINEERING | INARI AGRICULTURE TECHNOLOGY, INC. (US) | 2022-03-31 | — | — | WO | claimed |
| US-20220042117-A1 | COMPOSITIONS AND METHODS FOR THE SIMULTANEOUS DETECTION OF INFLUENZA A, INFLUENZA B, AND SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-CoV-2) | ROCHE MOLECULAR SYSTEMS, INC. | 2022-02-10 | — | — | US | claimed |
| WO-2022029157-A2 | COMPOSITIONS AND METHODS FOR THE DETECTION OF SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-2), INFLUENZA A, AND INFLUENZA B | F. HOFFMANN-LA ROCHE AG (CH) | 2022-02-10 | — | — | WO | claimed |
| US-20210199641-A1 | SINGLE-MOLECULE ELECTRONIC MULTIPLEX NANOPORE IMMUNOASSAYS FOR BIOMARKER DETECTION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-07-01 | — | — | US | claimed |
| EP-3826960-A1 | SINGLE-MOLECULE ELECTRONIC MULTIPLEX NANOPORE IMMUNOASSAYS FOR BIOMARKER DETECTION | The Trustees of Columbia University in the City of New York (US) | 2021-06-02 | — | — | EP | claimed |
| CN-108689907-B | Method for preparing 2-nitroindole derivative | 苏州大学 | 2020-05-01 | — | — | CN | claimed |
| US-8198423-B2 | High-risk human papillomavirus detection | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2012-06-12 | — | — | US | claimed |
| US-20120009564-A1 | High-Risk Human Papillomavirus Detection | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2012-01-12 | — | — | US | claimed |
| US-20120009562-A1 | High-Risk Human Papillomavirus Detection | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2012-01-12 | — | — | US | claimed |
| US-20120009563-A1 | High-Risk Human Papillomavirus Detection | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2012-01-12 | — | — | US | claimed |
| US-8058423-B2 | High-risk human papillomavirus detection | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2011-11-15 | — | — | US | claimed |
| EP-2035436-B1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2011-05-25 | — | — | EP | claimed |
| US-20090155773-A1 | High-Risk Human Papillomavirus Detection | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2009-06-18 | — | — | US | claimed |
| US-7482142-B1 | High-risk human papillomavirus detection | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2009-01-27 | — | — | US | claimed |
| US-20070031870-A1 | Methods and reagents for detecting target nucleic acids | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2007-02-08 | — | — | US | claimed |
| EP-1748083-A1 | Methods and reagents for detecting target nucleic acids | Roche Diagnostics GmbH (DE) | 2007-01-31 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12535477-B2 | Single-molecule electronic multiplex nanopore immunoassays for biomarker detection | EPCAM, CD47, SCNN1B | MAPT 3154/4885IDO1 4731/4885NPSR1 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.