⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodoacetamide SCHEMBL31146774 | 0.92 | — | — | |
| Iodoacetamide SCHEMBL27925562 | 0.92 | LMNA (1.00) | — | |
| Iodoacetamide SCHEMBL20371 | 0.92 | — | — | |
| Iodoacetamide SCHEMBL1332134 | 0.92 | — | — | |
| Iodoacetamide SCHEMBL4328107 | 0.89 | LMNA (0.79) | — | |
| Iodoacetamide SCHEMBL25246804 | 0.88 | — | — | |
| Iodoacetamide SCHEMBL2361208 | 0.88 | — | — | |
| Iodoacetamide SCHEMBL5993617 | 0.88 | — | — | |
| Iodoacetamide SCHEMBL8333021 | 0.88 | — | — | |
| Iodoacetamide SCHEMBL29006525 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180311377-A1 | DRUG DELIVERY SYSTEMS USING FC FRAGMENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-11-01 | — | — | US | disclosed |
| US-20100303723-A1 | DRUG DELIVERY SYSTEMS USING FC FRAGMENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-12-02 | — | — | US | disclosed |