Iodoacetamide

Iodoacetamide

SCHEMBL4328107

NC(=O)CI.O=C(O)CI

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.79
BLM P54132 3/20 0.79
ALDH1A1 P00352 2/20 0.79
CYP2C19 P33261 2/20 0.79
THPO P40225 2/20 0.79
TDP1 Q9NUW8 2/20 0.79
ALOX15 P16050 2/20 0.79
PMP22 Q01453 2/20 0.79
CYP1A2 P05177 2/20 0.79
KDM4E B2RXH2 1/20 0.79
GMNN O75496 1/20 0.79
USP2 O75604 1/20 0.79
TP53 P04637 1/20 0.79
GLA P06280 1/20 0.79
POLB P06746 1/20 0.79
CYP3A4 P08684 1/20 0.79
CYP2C9 P11712 1/20 0.79
HPGD P15428 1/20 0.79
RECQL P46063 1/20 0.79
HSD17B10 Q99714 1/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodoacetamide SCHEMBL3758504 0.89
Iodoacetamide SCHEMBL27925562 0.89 LMNA (1.00) LMNABLMALDH1A1CYP2C19THPO
Iodoacetamide SCHEMBL31146774 0.89
Iodoacetamide SCHEMBL20371 0.89
Iodoacetamide SCHEMBL1332134 0.89
Iodoacetamide SCHEMBL25246804 0.85
Iodoacetamide SCHEMBL29006525 0.85
Iodoacetamide SCHEMBL8333021 0.85
Iodoacetamide SCHEMBL5993617 0.85
Iodoacetamide SCHEMBL2361208 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1032709-A4 METHOD AND APPARATUS FOR PRESERVING HUMAN SALIVA FOR TESTING SCHNEIDER DAVID R (US) 2007-01-10 EP claimed
EP-1032709-A1 METHOD AND APPARATUS FOR PRESERVING HUMAN SALIVA FOR TESTING Schneider, David R. (US) 2000-09-06 EP claimed
WO-1999027139-A1 METHOD AND APPARATUS FOR PRESERVING HUMAN SALIVA FOR TESTING SCHNEIDER DAVID R (US) 1999-06-03 WO claimed
US-20210275646-A1 PHARMACOLOGIC TREATMENT FOR RIGHT VENTRICULAR FAILURE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2021-09-09 US disclosed
EP-2061518-A2 RADIOIMAGING MOIETIES COUPLED TO PEPTIDASE-BINDING MOIETIES FOR IMAGING TISSUES AND ORGANS THAT EXPRESS PEPTIDASES Molecular Insight Pharmaceuticals, Inc. (US) 2009-05-27 EP disclosed
WO-2008028000-A2 RADIOIMAGING MOIETIES COUPLED TO PEPTIDASE-BINDING MOIETIES FOR IMAGING TISSUES AND ORGANS THAT EXPRESS PEPTIDASES MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2008-03-06 WO disclosed
EP-0504363-B2 PURIFIED IgG ANTIBODIES WELLCOME FOUND (GB) 2007-02-07 EP disclosed
EP-0504363-B1 PURIFIED IgG ANTIBODIES WELLCOME FOUND (GB) 1998-01-21 EP disclosed
US-5644036-A Purified immunoglobulin BURROUGHS WELLCOME COMPANY (US) 1997-07-01 US disclosed
EP-0504363-A1 PURIFIED IgG ANTIBODIES THE WELLCOME FOUNDATION LIMITED (GB) 1992-09-23 EP disclosed
WO-1992007084-A1 PURIFIED CDW52-SPECIFIC ANTIBODIES THE WELLCOME FOUNDATION LIMITED (GB) 1992-04-30 WO disclosed