Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762710 | 1.00 | ESR1 (0.37) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL28632863 | 0.78 | ALOX15 (0.37) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL3870184 | 0.76 | KMT2A (0.36) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL3673620 | 0.76 | KMT2A (0.36) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL3673615 | 0.76 | KMT2A (0.36) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL3870186 | 0.76 | KMT2A (0.36) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL3673618 | 0.76 | KMT2A (0.36) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL3673617 | 0.76 | KMT2A (0.36) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL7593729 | 0.75 | — | — | |
| SCHEMBL7510499 | 0.72 | MMP2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7846701-B2 | Method for preparing optically active compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20070292925-A1 | Method for Preparing Optically Active Compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-12-20 | — | — | US | disclosed |
| EP-1813679-A1 | METHOD FOR PREPARING OPTICALLY ACTIVE COMPOUND | Takasago International Corporation (JP) | 2007-08-01 | — | — | EP | disclosed |