Styrene

Styrene

SCHEMBL3758847

C=CC(CC)C(=O)O.C=Cc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
PTGS2 P35354 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
CYP2C19 P33261 1/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
LMNA P02545 3/20 0.38
NPC1 O15118 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
AKR1C3 P42330 1/20 0.36
GLA P06280 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
GRIK1 P39086 1/20 0.36
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL6055991 0.84 LMNA (0.41) ALDH1A1TSHRCYP2C19MEN1KMT2A
Phthalic Acid SCHEMBL368309 0.82 ALDH1A1 (0.50) ALDH1A1CYP2C19MEN1KMT2AAKR1C3
SCHEMBL14533808 0.80
SCHEMBL26620 0.80
Styrene SCHEMBL27532687 0.79 ALDH1A1 (0.61) ALDH1A1TSHRPTGS2CYP2C19MEN1
Styrene SCHEMBL27500446 0.79 ALDH1A1 (0.61) ALDH1A1TSHRPTGS2CYP2C19LMNA
Styrene SCHEMBL27551584 0.79 ALDH1A1 (0.61) ALDH1A1TSHRTAS1R3TAS1R1CYP2C19
Styrene SCHEMBL7718194 0.79 ALDH1A1 (0.39) ALDH1A1TSHRPTGS2TAS1R3TAS1R1
Ethylene SCHEMBL3936195 0.78 TSHR (0.36) ALDH1A1TSHRCYP2C19MEN1KMT2A
Styrene SCHEMBL7745092 0.78 ALDH1A1 (0.54) ALDH1A1TSHRPTGS2CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7836630-B2 Method of protecting seeds treated with a phytotoxic agent MONSANTO TECHNOLOGY LLC (US) 2010-11-23 US claimed
EP-1566996-B1 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT MONSANTO TECHNOLOGY LLC (US) 2009-11-11 EP claimed
WO-2004049778-A9 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT MONSANTO TECHNOLOGY LLC (US) 2005-09-22 WO claimed
EP-1566996-A1 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT Monsanto Technology LLC (US) 2005-08-31 EP claimed
US-20040118040-A1 Method of protecting seeds treated with a phytotoxic agent MONSANTO TECHNOLOGY, L.L.C. 2004-06-24 US claimed
WO-2004049778-A1 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT MONSANTO TECHNOLOGY, LLC (US) 2004-06-17 WO claimed
EP-1566996-B1 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT MONSANTO TECHNOLOGY LLC (US) 2009-11-11 EP disclosed