SCHEMBL3759319

SCHEMBL3759319

Cc1cc(C)c(OP(=O)(OCl)OCl)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.43
TSHR P16473 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
SRC P12931 2/20 0.39
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7163824 0.96 CYP3A4 (0.43) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL218680 0.87 CYP3A4 (0.56) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL3628432 0.83 CYP3A4 (0.46) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL10883803 0.81 CYP3A4 (0.45) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL3757863 0.79 MAPT (0.40) CYP3A4TSHRALDH1A1MEN1KMT2A
SCHEMBL1913724 0.78 CYP3A4 (0.41) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL3759313 0.78 ALDH1A1 (0.41) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL10945329 0.75 SRC (0.47) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL4990431 0.75 MAPT (0.40) CYP3A4TSHRALDH1A1MEN1KMT2A
SCHEMBL27743221 0.75 HPGD (0.40) CYP3A4TSHRALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100298506-A1 METHOD FOR PRODUCING AN AMINO GROUP-CONTAINING PHOSPHATE COMPOUND, AND A FLAME-RETARDANT RESIN AND FLAME-RETARDANT RESIN COMPOSITION SHOWA HIGHPOLYMER CO., LTD. (JP) 2010-11-25 US disclosed
CN-101617014-A Flame-retardant adhesive composition, flexible copper-clad laminate and coverlay film SHOWA HIGHPOLYMER 2009-12-30 CN disclosed
CN-101460511-A Method for producing amino group-containing phosphate ester compound, flame-retardant resin, and flame-retardant resin composition SHOWA HIGHPOLYMER (JP) 2009-06-17 CN disclosed
EP-2036911-A1 PROCESS FOR PRODUCTION OF AMINATED PHOSPHORIC ACID ESTER COMPOUND, FLAME-RETARDANT RESIN, AND FLAME-RETARDANT RESIN COMPOSITION SHOWA HIGHPOLYMER CO., LTD. (JP) 2009-03-18 EP disclosed
US-4556684-A ADDING A ALKYL SUBSTITUTED TRIPHENYL PHOSPHATES FMC CORPORATION (US) 1985-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298506-A1 METHOD FOR PRODUCING AN AMINO GROUP-CONTAINING PHOSPHATE COMPOUND, AND A FLAME-RETARDANT RESIN AND FLAME-RETARDANT RESIN COMPOSITION ATIC, GART, RPP30 CYP3A4 2190/4885TSHR 2372/4885ALDH1A1 2459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.