SCHEMBL375936

SCHEMBL375936

Cc1ncnc2nc[nH]c12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LRRK2 Q5S007 2/20 0.57
PI4KA P42356 2/20 0.57
PI4K2B Q8TCG2 2/20 0.57
PI4K2A Q9BTU6 2/20 0.57
PI4KB Q9UBF8 2/20 0.57
LMNA P02545 2/20 0.57
DRD3 P35462 1/20 0.57
XDH P47989 1/20 0.57
PDPK1 O15530 2/20 0.57
TP53 P04637 2/20 0.57
HSD17B10 Q99714 2/20 0.57
CHEK1 O14757 1/20 0.57
AURKA O14965 1/20 0.57
CHEK2 O96017 1/20 0.57
HSP90AA1 P07900 1/20 0.57
HSP90AB1 P08238 1/20 0.57
PRKACA P17612 1/20 0.57
CCNE1 P24864 1/20 0.57
CDK2 P24941 1/20 0.57
MARK3 P27448 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Purine SCHEMBL731405 0.84 PDPK1 (0.44) LRRK2PI4KAPI4K2BPI4K2API4KB
SCHEMBL8083820 0.74 LRRK2 (0.53) LRRK2PI4KAPI4K2BPI4K2API4KB
SCHEMBL29522401 0.74 LRRK2 (0.53) LRRK2PI4KAPI4K2BPI4K2API4KB
SCHEMBL2008437 0.73 LMNA (0.57) LRRK2PI4KAPI4K2BPI4K2API4KB
Adenine SCHEMBL1331751 0.73 PI4KA (1.00) LRRK2PI4KAPI4K2BPI4K2API4KB
Adenine SCHEMBL3414606 0.73 PI4KA (1.00) LRRK2PI4KAPI4K2BPI4K2API4KB
SCHEMBL11491986 0.73 LMNA (0.57) LRRK2PI4KAPI4K2BPI4K2API4KB
SCHEMBL275945 0.73 LMNA (0.57) LRRK2PI4KAPI4K2BPI4K2API4KB
SCHEMBL532632 0.73 PI4KA (0.57) LRRK2PI4KAPI4K2BPI4K2API4KB
Adenine SCHEMBL8111 0.73 PI4KA (1.00) LRRK2PI4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1595 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680730-A2 COMPOSITIONS AND METHODS FOR INTERNEURON MEDIATED DELIVERY OF CYTOTOXIC AGENTS TO THE BRAIN The Children's Hospital Of Philadelphia (US) 2026-01-21 EP claimed
EP-4602052-A1 PROTEIN-BASED SIGNAL AMPLIFICATION California Institute of Technology (US) 2025-08-20 EP claimed
WO-2025151838-A1 SAFETY SWITCHES TO CONTROL IN VITRO AND IN VIVO PROLIFERATION OF CELL THERAPY PRODUCTS SANA BIOTECHNOLOGY, INC. (US) 2025-07-17 WO claimed
WO-2025097124-A1 MOLECULAR SWITCH FOR INDUCIBLE GENE EXPRESSION THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) 2025-05-08 WO claimed
WO-2025058093-A1 MODIFIED MITOCHONDRIA COMPRISING PRODRUG CONVERTING ENZYME AND USE THEREOF 주식회사 파이안바이오테크놀로지 2025-03-20 WO claimed
CN-112859550-B Aqueous phase developer for retarding aluminum corrosion and preparation method thereof 宁波南大光电材料有限公司 2024-11-29 CN claimed
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 CN claimed
WO-2024220831-A1 HYBRID SOYBEAN DONALD DANFORTH PLANT SCIENCE CENTER (US) 2024-10-24 WO claimed
CN-118772363-A Polyurethane/epoxy resin room-temperature rapid-curing material and preparation method and application thereof 青岛科技大学 2024-10-15 CN claimed
WO-2024196794-A2 COMPOSITIONS AND METHODS FOR INTERNEURON MEDIATED DELIVERY OF CYTOTOXIC AGENTS TO THE BRAIN THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2024-09-26 WO claimed
US-5563049-A 2',3'-dideoxy purine nucleosides and process for the preparation thereof NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-10-08 US claimed
WO-1996028190-A1 NON-INVASIVE IMAGING OF GENE TRANSFER SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1996-09-19 WO claimed
EP-0540686-B1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1995-08-30 EP claimed
EP-0365556-B1 NUCLEOSIDE ANALOGUES GENENTECH INC (US) 1995-07-12 EP claimed
EP-0540686-A4 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1993-05-26 EP claimed
EP-0540686-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. US COMMERCE (US) 1993-05-12 EP claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
EP-0399545-A2 Process for decontaminating cell cultures infested by mycoplasms BEHRINGWERKE Aktiengesellschaft (DE) 1990-11-28 EP claimed
EP-0098122-B1 PROCESSES FOR PRODUCING L-PROLINE BY FERMENTATION KYOWA HAKKO KOGYO CO., LTD. (JP) 1989-05-31 EP claimed
EP-0098122-A2 Processes for producing L-proline by fermentation KYOWA HAKKO KOGYO CO., LTD. (JP) 1984-01-11 EP claimed