Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.57 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.57 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | G6PD | P11413 | 1/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.52 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.52 |
| ▸ | MARK3 | P27448 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4865501 | 0.86 | PDPK1 (0.49) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL29692456 | 0.77 | LMNA (0.57) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL3414606 | 0.73 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL2008437 | 0.73 | LMNA (0.57) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL375936 | 0.73 | LRRK2 (0.57) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL8111 | 0.73 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL11491986 | 0.73 | LMNA (0.57) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL1331751 | 0.73 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Mercaptopurine Anhydrous SCHEMBL8844 | 0.73 | LMNA (0.57) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL275945 | 0.73 | LMNA (0.57) | PI4KAPI4K2BPI4K2API4KBLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773344-B | Method for synthesizing 2/6-iodopurine derivative through visible light induced hydrazine removal-iodination reaction | 新乡学院 | 2023-03-14 | — | — | CN | claimed |
| CN-114773344-A | Method for synthesizing 2/6-iodopurine derivative by visible light induced hydrazine removal-iodination reaction | 新乡学院 | 2022-07-22 | — | — | CN | claimed |
| CN-100490818-C | Methods for treating hepatitis delta virus infection with beta-L-2' deoxy-uncleosides | NOVARTIS AG (CH) | 2009-05-27 | — | — | CN | claimed |
| US-6316228-B1 | Efficient synthesis of nucleosides | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2001-11-13 | — | — | US | claimed |
| US-5817799-A | 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-10-06 | — | — | US | claimed |
| WO-1998017781-A1 | EFFICIENT SYNTHESIS OF NUCLEOSIDES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-04-30 | — | — | WO | claimed |
| EP-0540686-B1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | US COMMERCE (US) | 1995-08-30 | — | — | EP | claimed |
| EP-0540686-A4 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | US COMMERCE (US) | 1993-05-26 | — | — | EP | claimed |
| EP-0540686-A1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. | US COMMERCE (US) | 1993-05-12 | — | — | EP | claimed |
| WO-1992001700-A1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1992-02-06 | — | — | WO | claimed |
| CN-116693394-A | Dehydrazine method and application | 大连理工大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-114773344-B | Method for synthesizing 2/6-iodopurine derivative through visible light induced hydrazine removal-iodination reaction | 新乡学院 | 2023-03-14 | — | — | CN | disclosed |
| CN-114773344-B | Method for synthesizing 2/6-iodopurine derivative through visible light induced hydrazine removal-iodination reaction | 新乡学院 | 2023-03-14 | — | — | CN | disclosed |
| CN-114773344-B | Method for synthesizing 2/6-iodopurine derivative through visible light induced hydrazine removal-iodination reaction | 新乡学院 | 2023-03-14 | — | — | CN | disclosed |
| CN-114773344-A | Method for synthesizing 2/6-iodopurine derivative by visible light induced hydrazine removal-iodination reaction | 新乡学院 | 2022-07-22 | — | — | CN | disclosed |
| EP-0544668-A4 | 6-HALO- AND 2-AMINO-6-HALO-PURINE 2',3'-DIDEOXY NUCLEOSIDES AND THEIR USE AS ANTIVIRAL AGENTS. | US SECRETARY UNITED STATES DEP (JP) | 1993-03-03 | — | — | EP | disclosed |
| EP-0257488-B1 | Novel diaminopyrimido[4,5-d]pyrimidine glycoside and glycotide and process | WARNER-LAMBERT COMPANY (US) | 1992-04-29 | — | — | EP | disclosed |
| WO-1991012260-A1 | 6-HALO- AND 2-AMINO-6-HALO-PURINE 2',3'-DIDEOXY NUCLEOSIDES AND THEIR USE AS ANTIVIRAL AGENTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1991-08-22 | — | — | WO | disclosed |
| US-4801698-A | Process for preparing diaminopyrimido(4,5-d)pyrimidine glycoside and glycotide | WARNER-LAMBERT COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0257488-A2 | Novel diaminopyrimido[4,5-d]pyrimidine glycoside and glycotide and process | WARNER-LAMBERT COMPANY (US) | 1988-03-02 | — | — | EP | disclosed |