Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 17/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.71 |
| ▸ | MEN1 | O00255 | 13/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.58 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.58 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTR1E | P28566 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3682237 | 1.00 | MAPT (0.71) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3684656 | 0.88 | MAPT (0.66) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3763988 | 0.88 | MAPT (0.66) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3681296 | 0.87 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3762518 | 0.87 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3768960 | 0.81 | MAPT (0.53) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3681086 | 0.81 | MAPT (0.53) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL12443115 | 0.80 | CDK2 (0.58) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL6825490 | 0.80 | CDK2 (0.58) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL27424077 | 0.79 | LMNA (0.58) | MAPTKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426540-B2 | Tridentate ligand compounds with imino furan units, method for manufacturing said compounds, and their use in the preparation of catalysts for the homopolymerisation and copolymerisation of ethylene and alpha-olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-04-23 | — | — | US | claimed |
| US-20100311930-A1 | New Tridentate Ligand Compounds with Imino Furan Units, Method for Manufacturing Said Compounds, and their use in the Preparation of Catalysts for the Homopolymerisation and Copolymerisation of Ethylene and Alpha-Olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-12-09 | — | — | US | claimed |
| EP-2003125-A1 | NEW TRIDENTATE LIGAND COMPOUNDS WITH IMINO FURAN UNITS, METHOD FOR MANUFACTURING SAID COMPOUNDS, AND THEIR USE IN THE PREPARATION OF CATALYSTS FOR THE HOMOPOLYMERISATION AND COPOLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-12-17 | — | — | EP | claimed |
| US-8426540-B2 | Tridentate ligand compounds with imino furan units, method for manufacturing said compounds, and their use in the preparation of catalysts for the homopolymerisation and copolymerisation of ethylene and alpha-olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-04-23 | — | — | US | disclosed |
| US-20100311930-A1 | New Tridentate Ligand Compounds with Imino Furan Units, Method for Manufacturing Said Compounds, and their use in the Preparation of Catalysts for the Homopolymerisation and Copolymerisation of Ethylene and Alpha-Olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-12-09 | — | — | US | disclosed |
| EP-2003125-A1 | NEW TRIDENTATE LIGAND COMPOUNDS WITH IMINO FURAN UNITS, METHOD FOR MANUFACTURING SAID COMPOUNDS, AND THEIR USE IN THE PREPARATION OF CATALYSTS FOR THE HOMOPOLYMERISATION AND COPOLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311930-A1 | New Tridentate Ligand Compounds with Imino Furan Units, Method for Manufacturing Said Compounds, and their use in the Preparation of Catalysts for the Homopolymerisation and Copolymerisation of Ethylene and Alpha-Olefins | FDFT1, ETFB, ETFA | MAPT 1984/4885KMT2A 4413/4885MEN1 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.