Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157777 | 0.79 | HPGD (0.70) | KMT2ANPC1MEN1CYP1A2HPGD | |
| SCHEMBL70575 | 0.79 | KMT2A (0.56) | KMT2ANPC1MEN1CYP1A2HPGD | |
| SCHEMBL27770733 | 0.79 | KMT2A (0.36) | KMT2ANPC1MEN1CYP1A2HPGD | |
| SCHEMBL10413946 | 0.79 | CA12 (0.52) | KMT2AHPGDALDH1A1MAPK10LMNA | |
| SCHEMBL9710339 | 0.79 | CA12 (0.52) | KMT2ANPC1MEN1CYP1A2HPGD | |
| SCHEMBL6432535 | 0.78 | KMT2A (0.54) | KMT2ANPC1MEN1CYP1A2HPGD | |
| SCHEMBL9338313 | 0.78 | KMT2A (0.54) | KMT2ANPC1MEN1CYP1A2HPGD | |
| SCHEMBL13919867 | 0.78 | MAPT (0.56) | KMT2ANPC1MEN1CYP1A2HPGD | |
| SCHEMBL8115590 | 0.78 | KMT2A (0.54) | KMT2ANPC1MEN1CYP1A2HPGD | |
| SCHEMBL159806 | 0.78 | KMT2A (0.56) | KMT2ANPC1MEN1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 382 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535387-B | Photoresist main body resin synthesis intermediate and preparation method thereof | 沾化大荣化工科技有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-116535387-A | Photoresist main body resin synthesis intermediate and preparation method thereof | 沾化大荣化工科技有限公司 | 2023-08-04 | — | — | CN | claimed |
| JP-6025222-A | — | — | None | — | — | JP | disclosed |
| JP-8165289-A | — | — | None | — | — | JP | disclosed |
| US-12630561-B2 | Tricyclic derivatives inhibitor, preparation method, and applications thereof | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2026-05-19 | — | — | US | disclosed |
| EP-4676476-A1 | INHIBITORS OF TDP-43 AND TAU AGGREGATION | Aquinnah Pharmaceuticals, Inc. (US) | 2026-01-14 | — | — | EP | disclosed |
| US-20250302815-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC | 2025-10-02 | — | — | US | disclosed |
| EP-4551570-A1 | NOVEL COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Dong-A ST Co., Ltd. (KR) | 2025-05-14 | — | — | EP | disclosed |
| US-12297193-B2 | PTPN2/PTP1B degrader and therapeutic method thereof | NORTHRIDGE HEALTH GROUP (HONG KONG) CO., LIMITED (CN) | 2025-05-13 | — | — | US | disclosed |
| US-20250129058-A1 | PTPN2/PTP1B Degrader and Therapeutic Method Thereof | NORTHRIDGE HEALTH GROUP (HONG KONG) CO., LIMITED (CN) | 2025-04-24 | — | — | US | disclosed |
| WO-2025083594-A1 | PTPN2/PTP1B DEGRADER AND THERAPEUTIC METHOD THEREOF | NORTHRIDGE HEALTH GROUP (HONG KONG) CO., LIMITED (CN) | 2025-04-24 | — | — | WO | disclosed |
| US-4230873-A | Thiophene derivatives | HOFFMANN-LA ROCHE INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4224445-A | ANTIINFLAMMATORY, ANALGESIC, ANTIRHEUMATIC | HOFFMANN-LA ROCHE INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4177193-A | ALKOXYCARBONYL, ALKYLAMINOSULFONYL-SUBSTITUTED THIOPHENE INTERMEDIATES FOR THE 4-HYDROXY-N-SUBSTITUTED-2H-THIENO(2,3-E)-1,2-THIAZINE-3-CARBOXAMIDE-1,1 -DIOXIDES; ANTIINFLAMMATORY, ANALGESIC | HOFFMAN-LA ROCHE INC. (US) | 1979-12-04 | — | — | US | disclosed |
| US-4175085-A | ANTIINFLAMMATORY, ANALGESIC, ANTIRHEUMATIC | HOFFMANN-LA ROCHE INC. (US) | 1979-11-20 | — | — | US | disclosed |
| US-4134898-A | ANTIINFLAMMATORY, ANALGESIC, ANTIRHEUMATIC | HOFFMANN-LA ROCHE INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4119727-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1978-10-10 | — | — | US | disclosed |
| US-4090020-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIRHEUMATIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-05-16 | — | — | US | disclosed |
| US-4076709-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIRHEUMATIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4028373-A | ARTIFICIAL SWEETNERS | BASF AKTIENGESELLSCHAFT (DT) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12297193-B2 | PTPN2/PTP1B degrader and therapeutic method thereof | PTPN2, PTPN1, PTPN7 | KMT2A 988/4885NPC1 2549/4885MEN1 3634/4885 |
| US-20250302815-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | PTPN1, PTPN2, PTPN18 | KMT2A 1913/4885NPC1 2531/4885MEN1 3882/4885 |
| US-20250129058-A1 | PTPN2/PTP1B Degrader and Therapeutic Method Thereof | PTPN2, PTPN1, PTPN7 | KMT2A 988/4885NPC1 2549/4885MEN1 3634/4885 |
| US-12630561-B2 | Tricyclic derivatives inhibitor, preparation method, and applications thereof | PIK3CA, PIK3R1, PIK3CD | KMT2A 2280/4885NPC1 870/4885MEN1 3825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.