SCHEMBL159806

SCHEMBL159806

COC(=O)c1sccc1Cl

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.56
MEN1 O00255 5/20 0.56
POLB P06746 1/20 0.56
NPC1 O15118 1/20 0.53
SMN1; SMN2 Q16637 5/20 0.52
KDM4E B2RXH2 3/20 0.52
MAPT P10636 3/20 0.52
HPGD P15428 3/20 0.52
NPSR1 Q6W5P4 1/20 0.52
CYP1A2 P05177 1/20 0.51
TSHR P16473 1/20 0.51
ALDH1A1 P00352 4/20 0.50
RAB9A P51151 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13225705 0.81 KMT2A (0.50) KMT2AMEN1POLBNPC1SMN1; SMN2
SCHEMBL10480307 0.79 MAPK8 (0.48) KMT2AMEN1POLBMAPTHPGD
SCHEMBL11389102 0.79 MAPT (0.46) KMT2AMEN1POLBNPC1SMN1; SMN2
SCHEMBL240151 0.79 ALDH1A1 (0.49) KMT2AMEN1NPC1SMN1; SMN2KDM4E
SCHEMBL70575 0.78 KMT2A (0.56) KMT2AMEN1POLBNPC1SMN1; SMN2
SCHEMBL157777 0.78 HPGD (0.70) KMT2AMEN1NPC1SMN1; SMN2HPGD
SCHEMBL375957 0.78 KMT2A (0.56) KMT2AMEN1POLBNPC1SMN1; SMN2
SCHEMBL25304281 0.77 KMT2A (0.51) KMT2AMEN1POLBNPC1SMN1; SMN2
SCHEMBL155500 0.77
SCHEMBL23330285 0.77 KMT2A (0.45) KMT2AMEN1POLBMAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108031441-A There is the modified activated carbon absorbent of absorption property to the orthophosphates in water body 北京益清源环保科技有限公司 2018-05-15 CN claimed
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2026-04-16 US disclosed
EP-4714446-A2 PHARMACEUTICAL COMPOUNDS Nxera Pharma UK Limited (GB) 2026-03-25 EP disclosed
US-12416066-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2025-09-16 US disclosed
EP-4461833-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS Jetti Resources, LLC (US) 2024-11-13 EP disclosed
US-20240336990-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-10-10 US disclosed
US-20240336991-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-10-10 US disclosed
EP-4413985-A2 PHARMACEUTICAL COMPOUNDS Nxera Pharma UK Limited (GB) 2024-08-14 EP disclosed
US-12049680-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-07-30 US disclosed
US-12049681-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-07-30 US disclosed
US-4207089-A Thiolcarbamate derivatives of 3-trihalomethyl-1,2,4-thiadiazoles and their use as herbicides OLIN CORPORATION (US) 1980-06-10 US disclosed
US-4204858-A POST EMERGENCE HERBICIDES FOR RICE STAUFFER CHEMICAL COMPANY (US) 1980-05-27 US disclosed
US-4090865-A POSTEMERGENCE HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1978-05-23 US disclosed
US-4045208-A POST-EMERGENCE HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1977-08-30 US disclosed
US-4014924-A SELECTIVE HERBICIDES AND SOIL STERILANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-03-29 US disclosed
US-3976470-A HERBICIDE STAUFFER CHEMICAL COMPANY (US) 1976-08-24 US disclosed
US-3973947-A 1,3,5-Triazinediones and their use as selective herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-10 US disclosed
US-3971649-A HERBICIDE STAUFFER CHEMICAL COMPANY (US) 1976-07-27 US disclosed
US-3951971-A SELECTIVE HERBICIDES FUCHS JULIUS JAKOB 1976-04-20 US disclosed
US-3933469-A ALLOPHANIMIDATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS TST, FECH, SLC6A12 KMT2A 4070/4885MEN1 4130/4885POLB 3647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.