SCHEMBL3759765

SCHEMBL3759765

C#CCCCOc1cccc(CN(C(=O)O)C(C)(C)C)c1F

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 2/20 0.34
RIPK1 Q13546 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.32
GAA P10253 1/20 0.32
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
HRH1 P35367 1/20 0.31
KCNQ4 P56696 1/20 0.31
KCNQ5 Q9NR82 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
PTGES O14684 1/20 0.30
ALOX5 P09917 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3659959 0.75 KDM4E (0.37) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL3659957 0.75 KDM4E (0.40) L3MBTL1KDM4EALDH1A1MRGPRX4
SCHEMBL921790 0.75 RPS6KA1 (0.48) L3MBTL1KDM4EALDH1A1MEN1KMT2A
SCHEMBL3764508 0.74 HTR1B (0.35) L3MBTL1KDM4E
SCHEMBL3660767 0.73 KDM4E (0.34) L3MBTL1KDM4EALDH1A1KCNQ4KCNQ5
SCHEMBL2581913 0.73 POLQ (0.42) L3MBTL1KDM4EALDH1A1RIPK1GAA
Hydrochloric Acid SCHEMBL921369 0.73 KDM4E (0.37) L3MBTL1KDM4E
SCHEMBL1362694 0.72 MEN1 (0.41) L3MBTL1KDM4EALDH1A1RIPK1MEN1
SCHEMBL3759763 0.70 GRM2 (0.34) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL3770772 0.70 ADRB2 (0.34) L3MBTL1KDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 L3MBTL1 40/4885KDM4E 2021/4885ALDH1A1 2906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.