SCHEMBL3759913

SCHEMBL3759913

[Hf].c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.65
HPGD P15428 1/20 0.65
ALOX15 P16050 1/20 0.65
ALOX12 P18054 1/20 0.65
CASP1 P29466 1/20 0.65
HSD17B10 Q99714 1/20 0.65
MAOA P21397 4/20 0.63
MAOB P27338 3/20 0.63
TDP1 Q9NUW8 2/20 0.61
TAAR1 Q96RJ0 2/20 0.61
CYP2A6 P11509 1/20 0.61
HTR2A P28223 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
LOXL2 Q9Y4K0 1/20 0.61
KCNH2 Q12809 1/20 0.57
CALM1 P0DP23 1/20 0.56
FFAR1 O14842 1/20 0.55
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
SIGMAR1 Q99720 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9132387 0.96 MAOB (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL62125 0.96 ALDH1A1 (0.69) ALDH1A1HPGDALOX15ALOX12CASP1
Benzene SCHEMBL3440179 0.96 ALDH1A1 (0.69) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL9741303 0.96 ALDH1A1 (0.69) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL25403475 0.92 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
Hydrogen Sulfide SCHEMBL5468201 0.92 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL1793454 0.92 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL11747668 0.92 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL742615 0.92 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
Iodide SCHEMBL9705905 0.92 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110494458-A Alumoxane activated metallocene catalyst BOREALIS AG 2019-11-22 CN claimed
CN-110475793-A The metallocene catalyst of borate activatable BOREALIS AG 2019-11-19 CN claimed
EP-2285896-B2 High density polymer compositions, a method for their preparation and pressure-resistant pipes made therefrom BOREALIS AG (AT) 2019-10-16 EP claimed
CN-110337455-A The new catalyst system of polyethylene and ethylene copolymers is produced in high-temp. solution polymerization method 博里利斯股份公司 2019-10-15 CN claimed
CN-110234665-A Catalyst system for preparing polyethylene copolymers in high temperature solution polymerization process 博里利斯股份公司 2019-09-13 CN claimed
CN-1301272-A Catalyst system BASSEL POLYPROPYLENE GMBH (DE) 2001-06-27 CN claimed
EP-4735524-A1 ASPHALT COMPOSITION WITH AN IMPROVED LIFE SPAN SABIC Global Technologies B.V. (NL) 2026-05-06 EP disclosed
EP-4619475-A1 PAVING AND ROOFING COMPOSITE MATERIAL COMPRISING A BITUMEN, GROUND TIRE RUBBER AND A COMPATBILIZER SABIC Global Technologies B.V. (NL) 2025-09-24 EP disclosed
EP-4619466-A1 ASPHALT COMPOSITION WITH AN IMPROVED LIFE SPAN SABIC Global Technologies B.V. (NL) 2025-09-24 EP disclosed
US-12371448-B2 Post-metallocene compounds SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-07-29 US disclosed
CN-120051536-A Paving and roofing composite comprising asphalt, ground tire rubber, and compatibilizer SABIC环球技术有限责任公司 2025-05-27 CN disclosed
CN-119948096-A Asphalt mixture composition with improved service life SABIC环球技术有限责任公司 2025-05-06 CN disclosed
US-20250019469-A1 SOLUTION PROCESS FOR PRODUCTION OF FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-01-16 US disclosed
CN-1328580-A Bridged metallocenes for the copolymerization of olefins EXXON MOBIL CHEM PATENTS INC (US) 2001-12-26 CN disclosed
CN-1324370-A Olefin copolymerization process with bridged hafnocenes EXXON MOBIL CHEM PATENTS INC (US) 2001-11-28 CN disclosed
CN-1301272-A Catalyst system BASSEL POLYPROPYLENE GMBH (DE) 2001-06-27 CN disclosed
CN-1179735-A Bridged bis-amino group 4 metal compounds in catalyst composition SHELL INT RESEARCH (NL) 1998-04-22 CN disclosed
CN-1149879-A Process for preparing olefin polymer MITSUI PETROCHEMICAL IND (JP) 1997-05-14 CN disclosed
CN-1032008-C Addition polymerization catalyst with oxidative activation DOW CHEMICAL CO (US) 1996-06-12 CN disclosed
CN-1057845-A Addition polymerization catalyst with oxidation activity DOW CHEMICAL CO (US) 1992-01-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371448-B2 Post-metallocene compounds MRPS23, OPRM1, MRPL12 ALDH1A1 2511/4885HPGD 4050/4885ALOX15 1543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.