SCHEMBL376018

SCHEMBL376018

CC(C)(C)OC(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.61
PPARG P37231 4/20 0.58
ACE P12821 1/20 0.57
PPARD Q03181 2/20 0.53
KLK7 P49862 1/20 0.52
KLK5 Q9Y337 1/20 0.52
SYK P43405 1/20 0.52
CTSS P25774 4/20 0.52
CTSK P43235 3/20 0.51
CTSL P07711 1/20 0.50
CTSB P07858 1/20 0.50
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
KMT2A Q03164 1/20 0.49
FOLH1 Q04609 1/20 0.49
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL428113 1.00 PPARA (0.61) PPARAPPARGACEPPARDKLK7
SCHEMBL2009896 1.00 PPARA (0.61) PPARAPPARGACEPPARDKLK7
SCHEMBL13702217 0.95 PPARA (0.56) PPARAPPARGACEPPARDKLK7
SCHEMBL13702216 0.95 PPARA (0.56) PPARAPPARGACEPPARDKLK7
Dioxane SCHEMBL27814606 0.93 PPARA (0.54) PPARAPPARGACEPPARDKLK7
SCHEMBL8177426 0.93 PPARA (0.58) PPARAPPARGACEKLK7KLK5
SCHEMBL8178286 0.93 PPARA (0.58) PPARAPPARGACEKLK7KLK5
SCHEMBL1517760 0.93 PPARA (0.55) PPARAPPARGACEKLK7KLK5
SCHEMBL13007476 0.93 PPARA (0.55) PPARAPPARGACEKLK7KLK5
SCHEMBL2011835 0.93 PPARA (0.55) PPARAPPARGACEKLK7KLK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121575079-A SGLT1/2 double-target inhibitor, screening method and application thereof, and diabetes treatment drug 广东药科大学 2026-02-27 CN claimed
EP-4695257-A1 PROCESS FOR THE PREPARATION OF REMIMAZOLAM AND SALTS THEREOF Harman Finochem Limited (IN) 2026-02-18 EP claimed
WO-2024214109-A1 PROCESS FOR THE PREPARATION OF REMIMAZOLAM AND SALTS THEREOF HARMAN FINOCHEM LIMITED (IN) 2024-10-17 WO claimed
CN-111825742-B Polypeptide solid phase synthesis of CTPA as special coupling agent for amino acid ionic liquid 陈铭 2024-01-30 CN claimed
WO-2023148764-A1 NOVEL CHOLIC ACID DERIVATIVES FOR THE TREATMENT AND PREVENTION OF AUTOIMMUNE DISEASES AND USES THEREOF TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) 2023-08-10 WO claimed
CN-115490684-A 3S-1,2,3, 4-tetrahydro-beta-carboline-3-methyl-amino acid, preparation thereof, antithrombotic activity and application thereof 首都医科大学 2022-12-20 CN claimed
CN-115477648-A Carboline derivative, preparation method thereof and application thereof in preparing antitumor drugs 首都医科大学 2022-12-16 CN claimed
CN-109721522-A A kind of high-quality N- tertbutyloxycarbonyl-L-Glutimic acid benzyl ester industrialized preparing process 常州吉恩药业有限公司 2019-05-07 CN claimed
CN-102796171-B Double saturated aliphatic chain alcohol His-Gly-Glu-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL SCIENCES 2014-01-29 CN claimed
CN-102796171-A Double saturated aliphatic chain alcohol His-Gly-Glu-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL 2012-11-28 CN claimed
US-20260139257-A1 PLIN1 RNAi INTERFERENCE AGENTS ELI LILLY AND CO (US) 2026-05-21 US disclosed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN disclosed
EP-4725560-A2 ANTI-B7H3 ANTIBODIES FOR THE PREPARATION OF ANTIBODY DRUG CONJUGATES (ADCS) OF KSP INHIBITORS Bayer Pharma Aktiengesellschaft (DE) 2026-04-15 EP disclosed
CN-121575079-A SGLT1/2 double-target inhibitor, screening method and application thereof, and diabetes treatment drug 广东药科大学 2026-02-27 CN disclosed
EP-4695257-A1 PROCESS FOR THE PREPARATION OF REMIMAZOLAM AND SALTS THEREOF Harman Finochem Limited (IN) 2026-02-18 EP disclosed
EP-0482605-A2 HTLV-II derived peptide Kuraray Co., Ltd. (JP) 1992-04-29 EP disclosed
CN-1059725-A Novel methotrexate derivatives CHUGAI PHARMACEUTICAL CO LTD (JP) 1992-03-25 CN disclosed
EP-0474273-A2 A polypeptide capable of interacting with thrombin Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-03-11 EP disclosed
US-4629736-A HIGH FIBRINOLYTIC ACTION; WATER SOLUBILITY; ANTICOAGULANTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-12-16 US disclosed
EP-0136879-A2 Fatty acid derivatives and processes of producing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1985-04-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139257-A1 PLIN1 RNAi INTERFERENCE AGENTS PLIN1, PLIN3, PLIN5 PPARA 776/4885PPARG 1348/4885ACE 4562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.