Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.75 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907332 | 0.96 | TAAR1 (0.81) | TAAR1GRIN2BSIGMAR1GRIN1OPRM1 | |
| SCHEMBL3665298 | 0.94 | TAAR1 (0.84) | TAAR1GRIN2BSIGMAR1GRIN1OPRM1 | |
| SCHEMBL22216853 | 0.94 | TAAR1 (0.84) | TAAR1GRIN2BSIGMAR1GRIN1OPRM1 | |
| SCHEMBL21792273 | 0.94 | TAAR1 (0.84) | TAAR1GRIN2BSIGMAR1GRIN1OPRM1 | |
| SCHEMBL25002632 | 0.94 | TAAR1 (0.84) | TAAR1GRIN2BSIGMAR1GRIN1OPRM1 | |
| SCHEMBL24767088 | 0.94 | TAAR1 (0.84) | TAAR1GRIN2BSIGMAR1GRIN1OPRM1 | |
| SCHEMBL1240954 | 0.94 | TAAR1 (0.84) | TAAR1GRIN2BSIGMAR1GRIN1OPRM1 | |
| SCHEMBL24075499 | 0.94 | TAAR1 (0.84) | TAAR1GRIN2BSIGMAR1GRIN1OPRM1 | |
| SCHEMBL5332051 | 0.94 | TAAR1 (0.84) | TAAR1GRIN2BSIGMAR1GRIN1OPRM1 | |
| SCHEMBL662411 | 0.92 | GRIN2B (0.76) | TAAR1GRIN2BSIGMAR1GRIN1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867758-A | IRAK degradation agents and uses thereof | 凯麦拉医疗公司 | 2023-10-10 | — | — | CN | disclosed |
| US-8759584-B2 | Synthesis of biguanidines and triazines, and biguanidino-aluminium complexes as intermediates | BAYER CROPSCIENCE AG (DE) | 2014-06-24 | — | — | US | disclosed |
| US-20100305317-A1 | SYNTHESIS OF BIGUANIDINES AND TRIAZINES, AND BIGUANIDINO-ALUMINIUM COMPLEXES AS INTERMEDIATES | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2070934-A1 | Synthesis of biguanidines and triazines, and biguanidino-aluminium complexes as intermediates | Bayer CropScience AG (DE) | 2009-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305317-A1 | SYNTHESIS OF BIGUANIDINES AND TRIAZINES, AND BIGUANIDINO-ALUMINIUM COMPLEXES AS INTERMEDIATES | ATIC, SRM, F12 | TAAR1 43/4885GRIN2B 1261/4885SIGMAR1 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.