Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3771392 | 0.93 | KMT2A (0.56) | KMT2APLA2G1BATG4BMAPTTHRB | |
| SCHEMBL10633416 | 0.91 | THRB (0.62) | KMT2APLA2G1BATG4BMAPTTHRB | |
| SCHEMBL30354554 | 0.91 | THRB (0.62) | KMT2APLA2G1BATG4BMAPTTHRB | |
| SCHEMBL8384448 | 0.90 | ALDH1A1 (0.54) | KMT2APLA2G1BATG4BMAPTTHRB | |
| SCHEMBL11395782 | 0.89 | THRB (0.60) | KMT2AMAPTTHRBTDP1ALDH1A1 | |
| SCHEMBL6013651 | 0.89 | KMT2A (0.58) | KMT2APLA2G1BATG4BMAPTTHRB | |
| SCHEMBL11124363 | 0.89 | MAPT (0.55) | KMT2APLA2G1BATG4BMAPTTHRB | |
| SCHEMBL4905240 | 0.88 | KMT2A (0.62) | KMT2AMAPTTDP1ALDH1A1L3MBTL1 | |
| SCHEMBL11579348 | 0.88 | THRB (0.59) | KMT2AMAPTTHRBTDP1ALDH1A1 | |
| SCHEMBL28798935 | 0.88 | THRB (0.59) | KMT2AMAPTTHRBTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847998-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2010-12-07 | — | — | US | claimed |
| EP-2969499-A1 | METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION | Transitions Optical, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| CN-102668157-B | Organic electroluminescence element, manufacturing method thereof, and organic electroluminescence display device | SHARP KK | 2014-11-26 | — | — | CN | disclosed |
| WO-2014158802-A1 | METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION | TRANSITIONS OPTICAL, INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140265010-A1 | METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION | TRANSITIONS OPTICAL LIMITED (IE) | 2014-09-18 | — | — | US | disclosed |
| US-20140264979-A1 | METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION | TRANSITIONS OPTICAL LIMITED (IE) | 2014-09-18 | — | — | US | disclosed |
| US-20140078583-A1 | Photochromic Article Having At Least Partially Crossed Polarized Photochromic-Dichroic And Fixed-Polarized Layers | TRANSITIONS OPTICAL, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-8582192-B2 | Polarizing photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| CN-102668157-A | Organic electroluminescence element, manufacturing method thereof, and organic electroluminescence display device | SHARP KK | 2012-09-12 | — | — | CN | disclosed |
| US-7582749-B2 | Photochromic compounds | TRANSITIONS OPTICAL, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-20080123172-A1 | POLARIZING, PHOTOCHROMIC DEVICES AND METHODS OF MAKING THE SAME | TRANSITIONS OPTICAL LIMITED (IE) | 2008-05-29 | — | — | US | disclosed |
| US-20080096049-A1 | capable of switching between the two states in response to at least actinic radiation; thermally reversible | TRANSITIONS OPTICAL, INC. (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080096048-A1 | Thermally reversible; absorption ratio greater than 2.3 | TRANSITIONS OPTICAL, INC. (US) | 2008-04-24 | — | — | US | disclosed |
| US-7349137-B2 | Polarizing, photochromic devices and methods of making the same | PPG INDUSTRIES OHIO, INC. (US) | 2008-03-25 | — | — | US | disclosed |
| US-20080051575-A1 | capable of switching between the two states in response to at least actinic radiation; thermally reversible | TRANSITIONS OPTICAL ,INC. (US) | 2008-02-28 | — | — | US | disclosed |
| US-20080045704-A1 | Thermally reversible; absorption ratio greater than 2.3; cell method | TRANSITIONS OPTICAL, INC. (US) | 2008-02-21 | — | — | US | disclosed |
| US-7256921-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2007-08-14 | — | — | US | disclosed |
| US-20070053048-A1 | Polirizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-08 | — | — | US | disclosed |
| US-20050012998-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2005-01-20 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045704-A1 | Thermally reversible; absorption ratio greater than 2.3; cell method | CCND3, CCND1, CCND2 | KMT2A 1511/4885PLA2G1B 3900/4885ATG4B 4729/4885 |
| US-20080096048-A1 | Thermally reversible; absorption ratio greater than 2.3 | CCND1, CCND3, CCND2 | KMT2A 1838/4885PLA2G1B 3754/4885ATG4B 4705/4885 |
| US-20080051575-A1 | capable of switching between the two states in response to at least actinic radiation; thermally reversible | CCND1, CCND2, CCNE1 | KMT2A 1830/4885PLA2G1B 2027/4885ATG4B 4772/4885 |
| US-20080096049-A1 | capable of switching between the two states in response to at least actinic radiation; thermally reversible | CCND1, CCND2, CCNE1 | KMT2A 1830/4885PLA2G1B 2027/4885ATG4B 4772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.