SCHEMBL376074

SCHEMBL376074

CCCCCCCCCCCCCCCCO[Si](CC(C)CS)(OCCCCCCCCCCCCCCCC)OCCCCCCCCCCCCCCCC

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 3/20 0.33
LPAR3 Q9UBY5 3/20 0.33
DNM1 Q05193 1/20 0.32
SPHK1 Q9NYA1 1/20 0.31
USP2 O75604 1/20 0.31
HTT P42858 2/20 0.31
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375804 1.00 LPAR2 (0.33) LPAR2LPAR3DNM1SPHK1USP2
SCHEMBL375552 1.00 LPAR2 (0.33) LPAR2LPAR3DNM1SPHK1USP2
SCHEMBL375337 1.00 LPAR2 (0.33) LPAR2LPAR3DNM1SPHK1USP2
SCHEMBL375908 1.00 LPAR2 (0.33) LPAR2LPAR3DNM1SPHK1USP2
SCHEMBL375975 1.00 LPAR2 (0.33) LPAR2LPAR3DNM1SPHK1USP2
SCHEMBL376085 0.84
SCHEMBL375210 0.84 DNM1 (0.32) DNM1SPHK1USP2
SCHEMBL375709 0.84 DNM1 (0.32) DNM1SPHK1USP2
SCHEMBL376075 0.84 DNM1 (0.32) DNM1SPHK1USP2
SCHEMBL375670 0.84 DNM1 (0.32) DNM1SPHK1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518009-B2 Process for preparing mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2009-04-14 US claimed
US-20060252952-A1 Process for preparing mercaptoorganyl (alkoxysilanes) DEGUSSA AG (DE) 2006-11-09 US claimed
US-20140005432-A1 PROCESS FOR PREPARING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2014-01-02 US disclosed
EP-2408785-A1 PROCESS FOR PREPARING ORGANOSILANES Evonik Degussa GmbH (DE) 2012-01-25 EP disclosed
WO-2010105434-A1 PROCESS FOR PREPARING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2010-09-23 WO disclosed
US-7518009-B2 Process for preparing mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2009-04-14 US disclosed
US-7501534-B2 Process for the preparation of organosilanes DEGUSSA AG (DE) 2009-03-10 US disclosed
US-7339067-B2 Process for producing mercaptoorganyl (alkoxysilane) EVONIK DEGUSSA GMBH (DE) 2008-03-04 US disclosed
US-7332619-B2 Process for the preparation of mercaptoorganyl (alkoxysilanes) DEGUSSA AG (DE) 2008-02-19 US disclosed
EP-1700861-B1 Process for preparing organosilanes DEGUSSA (DE) 2007-08-15 EP disclosed
EP-1734045-B1 Process for preparing mercaptoorganyl alkoxy silanes DEGUSSA (DE) 2007-08-15 EP disclosed
EP-1637535-B1 Process for preparing mercaptoorganyl alkoxy silanes DEGUSSA (DE) 2007-02-28 EP disclosed
EP-1634884-B1 Process for preparing mercaptoorganyl alkoxy silanes DEGUSSA (DE) 2007-02-14 EP disclosed
EP-1734045-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa AG (DE) 2006-12-20 EP disclosed
US-20060252952-A1 Process for preparing mercaptoorganyl (alkoxysilanes) DEGUSSA AG (DE) 2006-11-09 US disclosed
US-20060204422-A1 Process for the preparation of organosilanes EVONIK OPERATIONS GMBH (DE) 2006-09-14 US disclosed
EP-1700861-A1 Process for preparing organosilanes Degussa GmbH (DE) 2006-09-13 EP disclosed
EP-1634884-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa GmbH (DE) 2006-03-15 EP disclosed
US-20060052622-A1 Process for the preparation of mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2006-03-09 US disclosed
US-20060052621-A1 Process for producing mercaptoorganyl (alkoxysilane) EVONIK DEGUSSA GMBH (DE) 2006-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140005432-A1 PROCESS FOR PREPARING ORGANOSILANES MPST, STS, CYP2S1 LPAR2 1773/4885LPAR3 3000/4885DNM1 4873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.