Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682194 | 0.94 | LMNA (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL14322259 | 0.83 | LMNA (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL7250811 | 0.83 | LMNA (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL28064250 | 0.83 | LMNA (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL1442288 | 0.83 | LMNA (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL2030994 | 0.83 | LMNA (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL4758861 | 0.83 | LMNA (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL7438483 | 0.83 | LMNA (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL20767099 | 0.83 | LMNA (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL27467045 | 0.83 | LMNA (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727720-B2 | Methods for detection of genetic disorders | RAVGEN, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| US-7442506-B2 | Methods for detection of genetic disorders | RAVGEN, INC. (US) | 2008-10-28 | — | — | US | disclosed |
| US-20070178478-A1 | Methods for detection of genetic disorders | RAVGEN, INC. | 2007-08-02 | — | — | US | disclosed |
| US-20060160105-A1 | Methods for detection of genetic disorders | RAVGEN, INC. (US) | 2006-07-20 | — | — | US | disclosed |
| US-20060121452-A1 | Methods for detection of genetic disorders | RAVGEN, INC. (US) | 2006-06-08 | — | — | US | disclosed |