SCHEMBL1682194

SCHEMBL1682194

NCCCCCC(=O)OC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.56
THRB P10828 2/20 0.56
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
ALDH1A1 P00352 1/20 0.56
PLG P00747 1/20 0.56
ALOX15 P16050 1/20 0.56
SLC6A2 P23975 1/20 0.56
RECQL P46063 1/20 0.56
SLC6A3 Q01959 1/20 0.56
NFKB1 P19838 2/20 0.52
CYP2D6 P10635 1/20 0.52
BLM P54132 3/20 0.50
NPSR1 Q6W5P4 2/20 0.50
PAOX Q6QHF9 2/20 0.48
CYP1A2 P05177 2/20 0.43
TSHR P16473 3/20 0.42
GABRR3 A8MPY1 1/20 0.42
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL3760865 0.94 LMNA (0.50) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL14322259 0.88 LMNA (0.56) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL7250811 0.88 LMNA (0.56) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL27467045 0.88 LMNA (0.56) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL1442288 0.88 LMNA (0.56) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL2030994 0.88 LMNA (0.56) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL4758861 0.88 LMNA (0.56) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL7438483 0.88 LMNA (0.56) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL20767099 0.88 LMNA (0.56) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL28064250 0.88 LMNA (0.56) LMNATHRBKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE Califia Pharma Inc. (US) 2023-11-23 US disclosed
CN-116762002-A Sensor for unbiased proteome studies, methods of making and using the same 纳米马赛克公司 2023-09-15 CN disclosed
US-11576876-B2 Affinity Medicant Conjugate AF CHEMICALS, LLC (US) 2023-02-14 US disclosed
US-20220133649-A1 AFFINITY MEDICANT CONJUGATE Califia Pharma Inc. (US) 2022-05-05 US disclosed
US-11241398-B2 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2022-02-08 US disclosed
US-11135182-B2 Affinity medicant conjugates AF CHEMICALS, LLC (US) 2021-10-05 US disclosed
US-20210299063-A1 AFFINITY MEDICANT CONJUGATE AF CHEMICALS, LLC (US) 2021-09-30 US disclosed
US-20210077425-A1 AFFINITY MEDICANT CONJUGATE AF CHEMICALS, LLC (US) 2021-03-18 US disclosed
WO-2013056096-A1 POLYPEPTIDE-OPIOID CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2013-04-18 WO disclosed
EP-2445523-A2 COMPOSITIONS AND METHODS FOR PREPARING STAPHYLOCOCCUS AUREUS SEROTYPE 5 AND 8 CAPSULAR POLYSACCHARIDE CONJUGATE IMMUNOGENIC COMPOSITIONS Wyeth LLC (US) 2012-05-02 EP disclosed
US-20110223645-A1 Multivalent Carriers of Bi-Specific Antibodies IMMUNOMEDICS, INC. (US) 2011-09-15 US disclosed
WO-2011041003-A9 COMPOSITIONS AND METHODS FOR PREPARING STAPHYLOCOCCUS AUREUS SEROTYPE 5 AND 8 CAPSULAR POLYSACCHARIDE CONJUGATE IMMUNOGENIC COMPOSITIONS WYETH LLC (US) 2011-06-09 WO disclosed
US-7951921-B2 Multivalent carriers of bi-specific antibodies IMMUNOMEDICS, INC. (US) 2011-05-31 US disclosed
WO-2011041003-A2 COMPOSITIONS AND METHODS FOR PREPARING STAPHYLOCOCCUS AUREUS SEROTYPE 5 AND 8 CAPSULAR POLYSACCHARIDE CONJUGATE IMMUNOGENIC COMPOSITIONS WYETH LLC (US) 2011-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210299063-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A LMNA 3666/4885THRB 3480/4885KMT2A 573/4885
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A LMNA 3666/4885THRB 3480/4885KMT2A 573/4885
US-20220133649-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A LMNA 3666/4885THRB 3480/4885KMT2A 573/4885
US-20110223645-A1 Multivalent Carriers of Bi-Specific Antibodies FCGR3B, FCGR2A, FCGR1A LMNA 4347/4885THRB 2068/4885KMT2A 2873/4885
US-11576876-B2 Affinity Medicant Conjugate FCER2, HDGF, FCGR2A LMNA 3666/4885THRB 3480/4885KMT2A 573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.