SCHEMBL3760952

SCHEMBL3760952

CCCCCN1CC(N)C(CO)C1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 6/20 0.61
GUSB P08236 2/20 0.49
EBP Q15125 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
GLB1 P16278 1/20 0.43
GBA2 Q9HCG7 3/20 0.39
GAA P10253 1/20 0.39
BCHE P06276 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL4565435 0.91 GBA1 (0.52) GBA1GUSBEBPSIGMAR1GNAI3
SCHEMBL3753688 0.80 GBA1 (0.78) GBA1GUSBGLB1GBA2GAA
SCHEMBL19098322 0.79 GBA1 (0.40) GBA1GAA
SCHEMBL2713123 0.77 GBA1 (0.97) GBA1GUSBGLB1GBA2GAA
SCHEMBL8186655 0.76 GBA1 (1.00) GBA1GUSBGLB1GBA2GAA
SCHEMBL8182808 0.76 GBA1 (1.00) GBA1GUSBGLB1GBA2GAA
SCHEMBL8182126 0.76 GBA1 (1.00) GBA1GUSBGLB1GBA2GAA
SCHEMBL8181038 0.76 GBA1 (1.00) GBA1GUSBGLB1GBA2GAA
SCHEMBL8181310 0.76 GBA1 (1.00) GBA1GUSBGLB1GBA2GAA
SCHEMBL2715246 0.76 GBA1 (1.00) GBA1GUSBGLB1GBA2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2112991-A1 NEW SYNTHONS FOR THE SYNTHESIS OF CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING THE SAME Nanodream S.r.l. Unipersonale (IT) 2009-11-04 EP claimed
WO-2008101515-A1 NEW SYNTHONS FOR THE SYNTHESIS OF CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING THE SAME NANODREAM S.R.L. UNIPERSONALE (IT) 2008-08-28 WO claimed
EP-2173738-A1 NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF VIRAL INFECTIONS AND METHODS FOR PREPARING THEM Nanodream S.r.l. Unipersonale (IT) 2010-04-14 EP disclosed
EP-2112991-A1 NEW SYNTHONS FOR THE SYNTHESIS OF CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING THE SAME Nanodream S.r.l. Unipersonale (IT) 2009-11-04 EP disclosed
WO-2008101515-A1 NEW SYNTHONS FOR THE SYNTHESIS OF CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING THE SAME NANODREAM S.R.L. UNIPERSONALE (IT) 2008-08-28 WO disclosed
WO-2008101514-A1 NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF VIRAL INFECTIONS AND METHODS FOR PREPARING THEM NANODREAM S.R.L. UNIPERSONALE (IT) 2008-08-28 WO disclosed