Pyrrolidine

Pyrrolidine

SCHEMBL4565435

C1CCNC1.CCCCCN1CC(N)C(CO)C1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 4/20 0.52
GUSB P08236 2/20 0.41
GNAO1 P09471 6/20 0.40
GNAI3 P08754 5/20 0.40
GNAI1 P63096 5/20 0.40
EBP Q15125 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
BCHE P06276 1/20 0.37
GLB1 P16278 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3760952 0.91 GBA1 (0.61) GBA1GUSBGNAO1GNAI3GNAI1
Piperidine SCHEMBL3378979 0.73 GUSB (0.70) GBA1GUSBGLB1
SCHEMBL3753688 0.73 GBA1 (0.78) GBA1GUSBGLB1
SCHEMBL19098322 0.71 GBA1 (0.40) GBA1
SCHEMBL2713123 0.70 GBA1 (0.97) GBA1GUSBGLB1
Piperidine SCHEMBL1859503 0.69 GLB1 (0.73) GBA1GUSBGLB1
SCHEMBL8181310 0.69 GBA1 (1.00) GBA1GUSBGLB1
SCHEMBL8186655 0.69 GBA1 (1.00) GBA1GUSBGLB1
SCHEMBL8182126 0.69 GBA1 (1.00) GBA1GUSBGLB1
SCHEMBL8181038 0.69 GBA1 (1.00) GBA1GUSBGLB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2112991-A1 NEW SYNTHONS FOR THE SYNTHESIS OF CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING THE SAME Nanodream S.r.l. Unipersonale (IT) 2009-11-04 EP disclosed
WO-2008101515-A1 NEW SYNTHONS FOR THE SYNTHESIS OF CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING THE SAME NANODREAM S.R.L. UNIPERSONALE (IT) 2008-08-28 WO disclosed